Renal tubular antigens in regenerative epithelium and renal carcinoma

S. Fleming; Tina J. Matthews

doi:10.1111/j.1464-410X.1987.tb04942.x

Renal tubular antigens in regenerative epithelium and renal carcinoma

S. Fleming, Tina J. Matthews

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

Antibodies to brush border antigen (BB) and epithelial membrane antigen (HMFG2) have been used in immunocytochemical preparations to define specific portions of the nephron. In both fetal and adult kidney BB was confined to the proximal tubule and HMFG2 to the distal tubule and collecting duct. The distribution of the antigens was studied in regenerative epithelium (15 cases) and renal carcinoma (35 cases). Regenerative epithelium in six cases expressed both antigens, and 29/35 renal carcinomas expressed both antigens. These results demonstrated some antigenic similarities between regenerative hyperplastic tubular epithelium and renal carcinoma.

Original language	English
Pages (from-to)	103-109
Number of pages	7
Journal	British Journal of Urology
Volume	60
Issue number	2
DOIs	https://doi.org/10.1111/j.1464-410X.1987.tb04942.x
Publication status	Published - 1987

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title = "Renal tubular antigens in regenerative epithelium and renal carcinoma",

abstract = "Antibodies to brush border antigen (BB) and epithelial membrane antigen (HMFG2) have been used in immunocytochemical preparations to define specific portions of the nephron. In both fetal and adult kidney BB was confined to the proximal tubule and HMFG2 to the distal tubule and collecting duct. The distribution of the antigens was studied in regenerative epithelium (15 cases) and renal carcinoma (35 cases). Regenerative epithelium in six cases expressed both antigens, and 29/35 renal carcinomas expressed both antigens. These results demonstrated some antigenic similarities between regenerative hyperplastic tubular epithelium and renal carcinoma.",

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AU - Fleming, S.

AU - Matthews, Tina J.

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AB - Antibodies to brush border antigen (BB) and epithelial membrane antigen (HMFG2) have been used in immunocytochemical preparations to define specific portions of the nephron. In both fetal and adult kidney BB was confined to the proximal tubule and HMFG2 to the distal tubule and collecting duct. The distribution of the antigens was studied in regenerative epithelium (15 cases) and renal carcinoma (35 cases). Regenerative epithelium in six cases expressed both antigens, and 29/35 renal carcinomas expressed both antigens. These results demonstrated some antigenic similarities between regenerative hyperplastic tubular epithelium and renal carcinoma.

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DO - 10.1111/j.1464-410X.1987.tb04942.x

M3 - Article

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VL - 60

SP - 103

EP - 109

JO - British Journal of Urology

JF - British Journal of Urology

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ER -

Renal tubular antigens in regenerative epithelium and renal carcinoma

Abstract

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