Renin-angiotensin system blockers are associated with reduced mortality and heart failure hospitalization in patients paced for complete atrioventricular block

Douglas H.J. Elder, Chim C. Lang, Sushma Rekhraj, Benjamin Szwejkowski, Jacob George, Stuart D. Pringle, Allan D. Struthers, Anna Maria Choy

    Research output: Contribution to journalArticle

    4 Citations (Scopus)

    Abstract

    Right ventricular apical pacing can cause dyssynchronous activation of the ventricles, increase sympathetic activation, cause abnormalities in myocardial perfusion, worsen cardiac output and endothelial function, and may be associated with adverse cardiovascular effects. The use of rennin–angiotensin system blockers (RASBs) may be beneficial in counteracting these potentially harmful effects of right ventricular pacing.
    Original languageEnglish
    Pages (from-to)505-510
    Number of pages6
    JournalHeart Rhythm : the Official Journal of the Heart Rhythm Society
    Volume9
    Issue number4
    DOIs
    Publication statusPublished - Apr 2012

    Fingerprint

    Atrioventricular Block
    Renin-Angiotensin System
    Cardiac Output
    Hospitalization
    Heart Failure
    Perfusion
    Mortality

    Keywords

    • pacemaker
    • survival
    • Heart failure
    • ACE Inhibitor
    • Angiotensin receptor blockers

    Cite this

    @article{4d7952a1176b47fcabb7a15c3cf4eb2f,
    title = "Renin-angiotensin system blockers are associated with reduced mortality and heart failure hospitalization in patients paced for complete atrioventricular block",
    abstract = "Right ventricular apical pacing can cause dyssynchronous activation of the ventricles, increase sympathetic activation, cause abnormalities in myocardial perfusion, worsen cardiac output and endothelial function, and may be associated with adverse cardiovascular effects. The use of rennin–angiotensin system blockers (RASBs) may be beneficial in counteracting these potentially harmful effects of right ventricular pacing.",
    keywords = "pacemaker, survival, Heart failure, ACE Inhibitor, Angiotensin receptor blockers",
    author = "Elder, {Douglas H.J.} and Lang, {Chim C.} and Sushma Rekhraj and Benjamin Szwejkowski and Jacob George and Pringle, {Stuart D.} and Struthers, {Allan D.} and Choy, {Anna Maria}",
    year = "2012",
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    doi = "10.1016/j.hrthm.2011.11.021",
    language = "English",
    volume = "9",
    pages = "505--510",
    journal = "Heart Rhythm : the Official Journal of the Heart Rhythm Society",
    issn = "1547-5271",
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    }

    Renin-angiotensin system blockers are associated with reduced mortality and heart failure hospitalization in patients paced for complete atrioventricular block. / Elder, Douglas H.J.; Lang, Chim C.; Rekhraj, Sushma; Szwejkowski, Benjamin; George, Jacob; Pringle, Stuart D.; Struthers, Allan D.; Choy, Anna Maria.

    In: Heart Rhythm : the Official Journal of the Heart Rhythm Society, Vol. 9, No. 4, 04.2012, p. 505-510.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Renin-angiotensin system blockers are associated with reduced mortality and heart failure hospitalization in patients paced for complete atrioventricular block

    AU - Elder, Douglas H.J.

    AU - Lang, Chim C.

    AU - Rekhraj, Sushma

    AU - Szwejkowski, Benjamin

    AU - George, Jacob

    AU - Pringle, Stuart D.

    AU - Struthers, Allan D.

    AU - Choy, Anna Maria

    PY - 2012/4

    Y1 - 2012/4

    N2 - Right ventricular apical pacing can cause dyssynchronous activation of the ventricles, increase sympathetic activation, cause abnormalities in myocardial perfusion, worsen cardiac output and endothelial function, and may be associated with adverse cardiovascular effects. The use of rennin–angiotensin system blockers (RASBs) may be beneficial in counteracting these potentially harmful effects of right ventricular pacing.

    AB - Right ventricular apical pacing can cause dyssynchronous activation of the ventricles, increase sympathetic activation, cause abnormalities in myocardial perfusion, worsen cardiac output and endothelial function, and may be associated with adverse cardiovascular effects. The use of rennin–angiotensin system blockers (RASBs) may be beneficial in counteracting these potentially harmful effects of right ventricular pacing.

    KW - pacemaker

    KW - survival

    KW - Heart failure

    KW - ACE Inhibitor

    KW - Angiotensin receptor blockers

    U2 - 10.1016/j.hrthm.2011.11.021

    DO - 10.1016/j.hrthm.2011.11.021

    M3 - Article

    VL - 9

    SP - 505

    EP - 510

    JO - Heart Rhythm : the Official Journal of the Heart Rhythm Society

    JF - Heart Rhythm : the Official Journal of the Heart Rhythm Society

    SN - 1547-5271

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    ER -