Replication forks, chromatin loops and dormant replication origins

J. Julian Blow, Xin Q Ge

    Research output: Contribution to journalReview articlepeer-review

    13 Citations (Scopus)

    Abstract

    When DNA replication is slowed down, normally dormant replication origins are activated. Recent work demonstrates that cells adapt by changing the organization of chromatin loops and maintaining the new pattern of origin use in subsequent cell cycles.

    Original languageEnglish
    Article number244
    Pages (from-to)-
    Number of pages4
    JournalGenome Biology
    Volume9
    Issue number12
    DOIs
    Publication statusPublished - 2008

    Keywords

    • DNA-REPLICATION
    • HUMAN-CELLS
    • CHROMOSOME STRUCTURE
    • REPLICON CLUSTERS
    • MAMMALIAN-CELLS
    • EXCESS MCM2-7
    • S PHASE
    • STRESS
    • ORGANIZATION
    • INHIBITION

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