Replication forks, chromatin loops and dormant replication origins

J. Julian Blow; Xin Q Ge

doi:10.1186/gb-2008-9-12-244

Replication forks, chromatin loops and dormant replication origins

J. Julian Blow
, Xin Q Ge

Research output: Contribution to journal › Review article › peer-review

15 Citations (Scopus)

Abstract

When DNA replication is slowed down, normally dormant replication origins are activated. Recent work demonstrates that cells adapt by changing the organization of chromatin loops and maintaining the new pattern of origin use in subsequent cell cycles.

Original language	English
Article number	244
Pages (from-to)	-
Number of pages	4
Journal	Genome Biology
Volume	9
Issue number	12
DOIs	https://doi.org/10.1186/gb-2008-9-12-244
Publication status	Published - 2008

Keywords

DNA-REPLICATION
HUMAN-CELLS
CHROMOSOME STRUCTURE
REPLICON CLUSTERS
MAMMALIAN-CELLS
EXCESS MCM2-7
S PHASE
STRESS
ORGANIZATION
INHIBITION

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10.1186/gb-2008-9-12-244

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title = "Replication forks, chromatin loops and dormant replication origins",

abstract = "When DNA replication is slowed down, normally dormant replication origins are activated. Recent work demonstrates that cells adapt by changing the organization of chromatin loops and maintaining the new pattern of origin use in subsequent cell cycles.",

keywords = "DNA-REPLICATION, HUMAN-CELLS, CHROMOSOME STRUCTURE, REPLICON CLUSTERS, MAMMALIAN-CELLS, EXCESS MCM2-7, S PHASE, STRESS, ORGANIZATION, INHIBITION",

author = "Blow, \{J. Julian\} and Ge, \{Xin Q\}",

year = "2008",

doi = "10.1186/gb-2008-9-12-244",

language = "English",

volume = "9",

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journal = "Genome Biology",

issn = "1474-7596",

publisher = "BioMed Central",

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TY - JOUR

T1 - Replication forks, chromatin loops and dormant replication origins

AU - Blow, J. Julian

AU - Ge, Xin Q

PY - 2008

Y1 - 2008

N2 - When DNA replication is slowed down, normally dormant replication origins are activated. Recent work demonstrates that cells adapt by changing the organization of chromatin loops and maintaining the new pattern of origin use in subsequent cell cycles.

AB - When DNA replication is slowed down, normally dormant replication origins are activated. Recent work demonstrates that cells adapt by changing the organization of chromatin loops and maintaining the new pattern of origin use in subsequent cell cycles.

KW - DNA-REPLICATION

KW - HUMAN-CELLS

KW - CHROMOSOME STRUCTURE

KW - REPLICON CLUSTERS

KW - MAMMALIAN-CELLS

KW - EXCESS MCM2-7

KW - S PHASE

KW - STRESS

KW - ORGANIZATION

KW - INHIBITION

U2 - 10.1186/gb-2008-9-12-244

DO - 10.1186/gb-2008-9-12-244

M3 - Review article

C2 - 19144207

SN - 1474-7596

VL - 9

SP - -

JO - Genome Biology

JF - Genome Biology

IS - 12

M1 - 244

ER -

Replication forks, chromatin loops and dormant replication origins

Abstract

Keywords

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