Repurposing metformin for cardiovascular disease

Projects

Projects per year 2013 2013 2014 2015 2016 2019

• 4 Finished

Projects per year

Search results

• Finished

  REnal and Cardiovascular Effects of SGLT2 Inhibition in Combination with Loop DiurEtics in Diabetic Patients with Chronic Heart Failure (RECEDE-CHF)

  Lang, C., McCrimmon, R., Mordi, I., Singh, J. & Struthers, A.

  British Heart Foundation

  29/07/16 → 28/01/19

  Project: Research

  • empagliflozin 100%
  • Sodium Potassium Chloride Symporter Inhibitors 87%
  • CHF protocol 80%
  • Heart Failure 47%
  • Sodium-Glucose Transport Proteins 45%

• Moving Towards a New Personalised Medicine Approach to Primary Prevention in Diabetes: The First Steps

  Dow, E., Lang, C., McCrimmon, R. & Struthers, A.

  5/08/15 → 4/09/17

  Project: Research

  • Metformin 100%
  • CHF protocol 77%
  • Left Ventricular Hypertrophy 66%
  • Coronary Artery Disease 64%
  • Symporters 56%

• MetfoRmin and its Effects on Myocardial Dimension and Left Ventricular Hypertrophy in Normotensive Patients with Coronary Artery Disease (MET-REMODEL Trial)

  George, J., Houston, G., Lang, C. & Struthers, A.

  British Heart Foundation

  1/10/14 → 31/12/17

  Project: Research

  • Metformin 100%
  • Coronary Artery Disease 67%
  • Ventricular Remodeling 55%
  • Left Ventricular Hypertrophy 50%
  • 2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol 48%

• Investigation of the Target of Metformin

  Prescott, A. & Rena, G.

  Medical Research Council

  1/05/13 → 30/04/16

  Project: Research

  • Metformin 100%
  • Pharmaceutical Preparations 38%
  • Type 2 Diabetes Mellitus 34%
  • Salicylates 29%
  • Equilibrative Nucleoside Transporter 1 27%