TY - JOUR
T1 - Reversal of Dose-Limiting Carboplatin-Induced Peripheral Neuropathy with TRPM8 Activator, Menthol, Enables Further Effective Chemotherapy Delivery
AU - Storey, Dawn J.
AU - Colvin, Lesley A.
AU - Mackean, Melanie J.
AU - Mitchell, Rory
AU - Fleetwood-Walker, Susan M.
AU - Fallon, Marie T.
PY - 2010/6
Y1 - 2010/6
N2 - Chemotherapy-induced peripheral neuropathy can be a major dose-limiting side effect and leave some cancer patients with long-term pain and functional disability. In some cases, the neuropathy can be so severe as to preclude further life-prolonging chemotherapy. It is important to find interventions to reduce such effects while enabling effective chemotherapy dose delivery, improved survival, and good quality of life.
AB - Chemotherapy-induced peripheral neuropathy can be a major dose-limiting side effect and leave some cancer patients with long-term pain and functional disability. In some cases, the neuropathy can be so severe as to preclude further life-prolonging chemotherapy. It is important to find interventions to reduce such effects while enabling effective chemotherapy dose delivery, improved survival, and good quality of life.
UR - http://www.scopus.com/inward/record.url?scp=77953109127&partnerID=8YFLogxK
U2 - 10.1016/j.jpainsymman.2010.02.004
DO - 10.1016/j.jpainsymman.2010.02.004
M3 - Letter
C2 - 20538177
AN - SCOPUS:77953109127
SN - 0885-3924
VL - 39
SP - e2-e4
JO - Journal of Pain and Symptom Management
JF - Journal of Pain and Symptom Management
IS - 6
ER -
