Reversible striatal hypermetabolism in a case of Sydenham's chorea

Serge Goldman, Dina Amron, Henri B. Szliwowski, Dominique Detemmerman, Sylvie Goldman, Luc M. Bidaut, Etienne Stanus, André Luxen

    Research output: Contribution to journalArticlepeer-review

    66 Citations (Scopus)


    We studied a 10-year-old girl with Sydenham's chorea (SC) using positron emission tomography (PET) with fluorodeoxyglucose (FDG). Choreic movements involved the head and the left side of her body. PET showed increased glucose metabolism in the right caudate nucleus and putamen. Three months after complete recovery, striatal glucose metabolism had returned to normal in the caudate nucleus. In the right putamen, glucose metabolism had decreased compared to that in the first study but remained elevated compared to that of normal young adults. We propose that the transient striatal hypermetabolism may have been due to increased afferent inputs to the striatum as a consequence of striatal or subthalamic nucleus dysfunction.
    Original languageEnglish
    Pages (from-to)355-358
    Number of pages4
    JournalMovement Disorders
    Issue number3
    Publication statusPublished - 1993


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