TY - JOUR
T1 - Reversible striatal hypermetabolism in a case of Sydenham's chorea
AU - Goldman, Serge
AU - Amron, Dina
AU - Szliwowski, Henri B.
AU - Detemmerman, Dominique
AU - Goldman, Sylvie
AU - Bidaut, Luc M.
AU - Stanus, Etienne
AU - Luxen, André
PY - 1993
Y1 - 1993
N2 - We studied a 10-year-old girl with Sydenham's chorea (SC) using positron emission tomography (PET) with fluorodeoxyglucose (FDG). Choreic movements involved the head and the left side of her body. PET showed increased glucose metabolism in the right caudate nucleus and putamen. Three months after complete recovery, striatal glucose metabolism had returned to normal in the caudate nucleus. In the right putamen, glucose metabolism had decreased compared to that in the first study but remained elevated compared to that of normal young adults. We propose that the transient striatal hypermetabolism may have been due to increased afferent inputs to the striatum as a consequence of striatal or subthalamic nucleus dysfunction.
AB - We studied a 10-year-old girl with Sydenham's chorea (SC) using positron emission tomography (PET) with fluorodeoxyglucose (FDG). Choreic movements involved the head and the left side of her body. PET showed increased glucose metabolism in the right caudate nucleus and putamen. Three months after complete recovery, striatal glucose metabolism had returned to normal in the caudate nucleus. In the right putamen, glucose metabolism had decreased compared to that in the first study but remained elevated compared to that of normal young adults. We propose that the transient striatal hypermetabolism may have been due to increased afferent inputs to the striatum as a consequence of striatal or subthalamic nucleus dysfunction.
UR - http://www.scopus.com/inward/record.url?scp=0027317770&partnerID=8YFLogxK
U2 - 10.1002/mds.870080318
DO - 10.1002/mds.870080318
M3 - Article
AN - SCOPUS:0027317770
SN - 0885-3185
VL - 8
SP - 355
EP - 358
JO - Movement Disorders
JF - Movement Disorders
IS - 3
ER -