Review article: population screening for colorectal cancer

F. B. Nicholson, J. L. Barro, R. Lilford, W. Atkin, J. Patnick, C. B. Williams, M. Pignone, R. Steele, M. A. Kamm (Lead / Corresponding author)

    Research output: Contribution to journalArticlepeer-review

    33 Citations (Scopus)


    Colorectal cancer is a common cancer and common cause of death. The mortality rate from colorectal cancer can be reduced by identification and removal of cancer precursors, adenomas, or by detection of cancer at an earlier stage.
    Pilot screening programmes have demonstrated decreased colorectal cancer mortality; as a result many countries are developing colorectal cancer screening programmes. The most common modalities being evaluated are faecal occult blood testing, flexible sigmoidoscopy and colonoscopy. Implementation of screening tests has been hampered by cost, invasiveness, availability of resources and patient acceptance. New technologies such at computed tomographic colonography and stool screening for molecular markers of neoplasia are in development as potential minimally invasive tools.
    This review considers who should be screened, which test to use and how often to screen.
    Original languageEnglish
    Pages (from-to)1069-1077
    Number of pages9
    JournalAlimentary Pharmacology & Therapeutics
    Issue number11-12
    Early online date14 Nov 2005
    Publication statusPublished - Dec 2005


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