Projects per year
Abstract
Ribozymes are excellent systems in which to study 'sequence - structure - function' relationships in RNA molecules. Understanding these relationships may greatly help structural modeling and design of functional RNA structures and some functional structural modules could be repurposed in molecular design. At present, there is no comprehensive database summarising all the natural ribozyme families. We have therefore created Ribocentre, a database that collects together sequence, structure and mechanistic data on 21 ribozyme families. This includes available information on timelines, sequence families, secondary and tertiary structures, catalytic mechanisms, applications of the ribozymes together with key publications. The database is publicly available at https://www.ribocentre.org.
Original language | English |
---|---|
Pages (from-to) | D262-D268 |
Number of pages | 7 |
Journal | Nucleic Acids Research |
Volume | 51 |
Issue number | D1 |
Early online date | 30 Sept 2022 |
DOIs | |
Publication status | Published - 6 Jan 2023 |
Fingerprint
Dive into the research topics of 'Ribocentre: a database of ribozymes'. Together they form a unique fingerprint.Projects
- 1 Finished
-
The Nucleic Acid Structure Research Group
Lilley, D. (Investigator)
1/01/16 → 31/12/22
Project: Research