Risk of diabetic retinopathy at first screen in children at 12 and 13 years of age

P. H. Scanlon (Lead / Corresponding author), I. M. Stratton, M. O. Bachmann, C. Jones, G. P. Leese, The Four Nations Diabetic Retinopathy Screening Study Group

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)
181 Downloads (Pure)

Abstract

AIMS: To investigate the relationships between age at diagnosis of diabetes, age at diabetic eye screening and severity of diabetic retinopathy at first and subsequent screenings in children aged 12 or 13 years.

METHODS: Data were extracted from four English screening programmes and from the Scottish, Welsh and Northern Irish programmes on all children with diabetes invited for their first and subsequent screening episodes from the age of 12 years. Retinopathy levels at first and subsequent screens, time from diagnosis of diabetes to first screening and age at diagnosis in years were calculated.

RESULTS: Data were available for 2125 children with diabetes screened for the first time at age 12 or 13 years. In those diagnosed with diabetes at 2 years of age or less, the proportion with retinopathy in one or both eyes was 20% and 11%, respectively, decreasing to 8% and 2% in those diagnosed between 2 and 12 years (P < 0.0001). Only three children (aged 8, 10 and 11 years at diagnosis of diabetes) had images graded with referable retinopathy and, of these, two had non-referable diabetic retinopathy at all subsequent screenings. Of 1703 children with subsequent images, 25 were graded with referable diabetic retinopathy over a mean follow-up of 3.1 years, an incidence rate of 4.7 (95% confidence interval, 3.1-7.0) per 1000 per year.

CONCLUSIONS: In this large cohort of children, the low prevalence and incidence rates of referable diabetic retinopathy suggest that screening earlier than age 12 is not necessary. This article is protected by copyright. All rights reserved.

Original languageEnglish
Pages (from-to)1655-1658
Number of pages4
JournalDiabetic Medicine
Volume33
Issue number12
Early online date20 Sep 2016
DOIs
Publication statusPublished - 19 Oct 2016

Fingerprint Dive into the research topics of 'Risk of diabetic retinopathy at first screen in children at 12 and 13 years of age'. Together they form a unique fingerprint.

Cite this