RNA folding and the origins of catalytic activity in the hairpin ribozyme

Keyphrases

• Catalytic Activity 100%
• Ligation 100%
• Hairpin Ribozyme 100%
• RNA Folding 100%
• Ribozyme 66%
• Ligation Reactions 66%
• PH Dependence 66%
• Local Environment 33%
• Cleavage Reactions 33%
• Nucleobases 33%
• Ribozyme Catalysis 33%
• Nucleolytic Ribozymes 33%
• Single-molecule Fluorescence Resonance Energy Transfer (smFRET) 33%
• Helical Junction 33%
• Four-way 33%
• Ion-induced 33%
• Induced Folding 33%
• Ribonucleosides 33%
• Titration 33%
• Imidazole 33%
• Bell-shaped 33%
• Acid-base Catalysis 33%
• Transesterification Reaction 33%
• Undocking 33%
• Phosphodiester Cleavage 33%
• Internal Reaction 33%
• Loop-loop Interaction 33%
• Dissociation Mechanism 33%

Chemistry

• RNA 100%
• Catalyst Activity 100%
• Fluorescence Resonance Energy Transfer 50%
• Nucleobase 50%
• Imidazole 50%
• Acid-Base Catalysis 50%
• Transesterification 50%
• smFRET Spectroscopy 50%
• Ribonucleoside 50%

Biochemistry, Genetics and Molecular Biology

• Ribozyme 100%
• RNA Folding 100%
• Enzymatic Activity 100%
• Fluorescence Resonance Energy Transfer 33%
• RNA 16%
• Nucleobase 16%
• Functional Dissociation 16%
• Ribonucleoside 16%
• Transesterification 16%