Abstract
RNA molecules play an essential role in many cellular processes, often as components of ribonucleoprotein complexes. Like proteins, RNA molecules adopt sequence-specific secondary and tertiary structures that are essential for function; alteration of these structures therefore provides a means of regulating RNA function. The discovery of DEAD box proteins, a large family of proteins that share several highly conserved motifs and have known or putative ATP-dependent RNA helicase activity, has provoked growing interest in the concept that regulation of RNA function may occur through local unwinding of complex RNA structures.
| Original language | English |
|---|---|
| Pages (from-to) | 271-274 |
| Number of pages | 4 |
| Journal | Trends in Cell Biology |
| Volume | 4 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - Aug 1994 |
Fingerprint
Cite this
}
RNA helicases : modulators of RNA structure. / Fuller-Pace, Frances V.
In: Trends in Cell Biology, Vol. 4, No. 8, 08.1994, p. 271-274.Research output: Contribution to journal › Article
TY - JOUR
T1 - RNA helicases
T2 - modulators of RNA structure
AU - Fuller-Pace, Frances V.
PY - 1994/8
Y1 - 1994/8
N2 - RNA molecules play an essential role in many cellular processes, often as components of ribonucleoprotein complexes. Like proteins, RNA molecules adopt sequence-specific secondary and tertiary structures that are essential for function; alteration of these structures therefore provides a means of regulating RNA function. The discovery of DEAD box proteins, a large family of proteins that share several highly conserved motifs and have known or putative ATP-dependent RNA helicase activity, has provoked growing interest in the concept that regulation of RNA function may occur through local unwinding of complex RNA structures.
AB - RNA molecules play an essential role in many cellular processes, often as components of ribonucleoprotein complexes. Like proteins, RNA molecules adopt sequence-specific secondary and tertiary structures that are essential for function; alteration of these structures therefore provides a means of regulating RNA function. The discovery of DEAD box proteins, a large family of proteins that share several highly conserved motifs and have known or putative ATP-dependent RNA helicase activity, has provoked growing interest in the concept that regulation of RNA function may occur through local unwinding of complex RNA structures.
UR - http://www.scopus.com/inward/record.url?scp=0028301073&partnerID=8YFLogxK
U2 - 10.1016/0962-8924(94)90210-0
DO - 10.1016/0962-8924(94)90210-0
M3 - Article
AN - SCOPUS:0028301073
VL - 4
SP - 271
EP - 274
JO - Trends in Cell Biology
JF - Trends in Cell Biology
SN - 0962-8924
IS - 8
ER -