RNA helicases: modulators of RNA structure

TY - JOUR

T1 - RNA helicases

T2 - modulators of RNA structure

AU - Fuller-Pace, Frances V.

PY - 1994/8

Y1 - 1994/8

N2 - RNA molecules play an essential role in many cellular processes, often as components of ribonucleoprotein complexes. Like proteins, RNA molecules adopt sequence-specific secondary and tertiary structures that are essential for function; alteration of these structures therefore provides a means of regulating RNA function. The discovery of DEAD box proteins, a large family of proteins that share several highly conserved motifs and have known or putative ATP-dependent RNA helicase activity, has provoked growing interest in the concept that regulation of RNA function may occur through local unwinding of complex RNA structures.

AB - RNA molecules play an essential role in many cellular processes, often as components of ribonucleoprotein complexes. Like proteins, RNA molecules adopt sequence-specific secondary and tertiary structures that are essential for function; alteration of these structures therefore provides a means of regulating RNA function. The discovery of DEAD box proteins, a large family of proteins that share several highly conserved motifs and have known or putative ATP-dependent RNA helicase activity, has provoked growing interest in the concept that regulation of RNA function may occur through local unwinding of complex RNA structures.

UR - https://www.scopus.com/pages/publications/0028301073

U2 - 10.1016/0962-8924(94)90210-0

DO - 10.1016/0962-8924(94)90210-0

M3 - Article

AN - SCOPUS:0028301073

SN - 0962-8924

VL - 4

SP - 271

EP - 274

JO - Trends in Cell Biology

JF - Trends in Cell Biology

IS - 8

ER -