RNA polymerase II transcription in living color

Angus I. Lamond (Lead / Corresponding author), Jason R. Swedlow

    Research output: Contribution to journalShort surveypeer-review

    3 Citations (Scopus)

    Abstract

    Using a previously developed method, Singer and co-workers have now labeled RNA transcripts and quantitatively measured the synthesis of RNA in living cells. They find that only a small fraction of the RNA polymerases that bind the promoter actually produce messenger RNA. They also observed much faster elongation than previously reported, along with frequent long pauses.

    Original languageEnglish
    Pages (from-to)788-790
    Number of pages3
    JournalNature Structural and Molecular Biology
    Volume14
    Issue number9
    DOIs
    Publication statusPublished - 1 Sep 2007

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