Roles of glycans in protozoal host-parasite interactions

Giulia Bandini, Michael A.J. Ferguson

Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary


Protozoan parasites are an extremely diverse group of organisms that affect human health worldwide. Glycans can play key roles in parasite virulence and they are often found at the center of the strategies these pathogens have evolved to interact with their hosts and transmission vectors. Here we describe some of the best characterized examples of glycan-mediated host-parasite interactions. The aim is to illustrate the spectrum of mechanisms and biomolecular structures employed by parasites to (1) recognize and attach to the host, (2) evade and modulate the immune response, and (3) build protective walls using glycans and glycan-binding proteins.

Original languageEnglish
Title of host publicationEncyclopedia of Cell Biology
EditorsRalph A. Bradshaw, Gerald W. Hart, Philip D. Stahl
Place of PublicationLondon
Number of pages10
ISBN (Electronic)9780128216248
Publication statusPublished - 2023


  • Glycan-binding proteins
  • Glycobiology
  • Glycoconjugates
  • Glycomimicry
  • Host-parasite interactions
  • Immune evasion
  • Lectins
  • Protists
  • Protozoan parasites
  • Scaffolding

ASJC Scopus subject areas

  • General Biochemistry,Genetics and Molecular Biology


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