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Abstract
Posterior fossa ependymomas (PFEs) are designated histologically as low-grade neoplasms. Despite being characterised as benign, cases of metastasis have been reported only a few times with the patients concurrently diagnosed with the primary tumour. Interval drop metastasis or spontaneous second distal tumours are extremely rare and, in most cases, are diagnosed within a few months of primary tumour resection. Here, we report a patient with a grade 2 paediatric PFE exhibiting a 20-year interval to a second sacral ependymoma. The patient was initially diagnosed with a PFE at the age of 10 years and underwent tumour resection and postoperative radiotherapy. In their late 20s, the patient presented with basilar artery occlusion complicated by life-threatening epistaxis. Post-thrombolysis, the patient presented with a large sacral grade 1 myxopapillary ependymoma with cauda equina syndrome-like symptoms. Here, we present a rare case of two ependymomas with a 20-year interval in the same patient with compounding comorbidities.
Original language | English |
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Article number | e256611 |
Number of pages | 4 |
Journal | BMJ Case Reports |
Volume | 16 |
Issue number | 10 |
DOIs | |
Publication status | Published - 19 Oct 2023 |
Keywords
- Humans
- Child
- Ependymoma/diagnosis
- Magnetic Resonance Imaging
- Neoplasm Recurrence, Local/surgery
- Spinal Cord Neoplasms/complications
- Cancer intervention
- Stroke
- Radiology
- Neurooncology
ASJC Scopus subject areas
- General Medicine
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A Single Kinase Modulates The Diverse Extracellular Phosphoproteome Of Glioblastoma Multiforme
Banerjee, S. (Investigator)
1/08/22 → 31/07/26
Project: Research