Sacral ependymoma presents 20 years after initial posterior fossa lesion

Lynden Guy Nicely, Mark Baxter, Sourav Banerjee (Lead / Corresponding author), Hannah Lord (Lead / Corresponding author)

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    1 Citation (Scopus)
    38 Downloads (Pure)

    Abstract

    Posterior fossa ependymomas (PFEs) are designated histologically as low-grade neoplasms. Despite being characterised as benign, cases of metastasis have been reported only a few times with the patients concurrently diagnosed with the primary tumour. Interval drop metastasis or spontaneous second distal tumours are extremely rare and, in most cases, are diagnosed within a few months of primary tumour resection. Here, we report a patient with a grade 2 paediatric PFE exhibiting a 20-year interval to a second sacral ependymoma. The patient was initially diagnosed with a PFE at the age of 10 years and underwent tumour resection and postoperative radiotherapy. In their late 20s, the patient presented with basilar artery occlusion complicated by life-threatening epistaxis. Post-thrombolysis, the patient presented with a large sacral grade 1 myxopapillary ependymoma with cauda equina syndrome-like symptoms. Here, we present a rare case of two ependymomas with a 20-year interval in the same patient with compounding comorbidities.

    Original languageEnglish
    Article numbere256611
    Number of pages4
    JournalBMJ Case Reports
    Volume16
    Issue number10
    DOIs
    Publication statusPublished - 19 Oct 2023

    Keywords

    • Humans
    • Child
    • Ependymoma/diagnosis
    • Magnetic Resonance Imaging
    • Neoplasm Recurrence, Local/surgery
    • Spinal Cord Neoplasms/complications
    • Cancer intervention
    • Stroke
    • Radiology
    • Neurooncology

    ASJC Scopus subject areas

    • General Medicine

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