Secondary flow in peripheral vascular prosthetic grafts using vector Doppler imaging

Efstratios Kokkalis (Lead / Corresponding author), Peter R. Hoskins, George A. Corner, Peter A. Stonebridge, Anthony J. Doull, J. Graeme Houston

    Research output: Contribution to journalArticlepeer-review

    11 Citations (Scopus)


    Prosthetic grafts are used for the treatment of peripheral arterial disease. Re-stenosis in the distal anastomosis of these grafts is a common reason for graft occlusion. The role of local hemodynamics in development of neo-intimal hyperplasia is well known. A new graft design has been proposed for the induction of optimized spiral flow in the host vessel. The secondary flow motions induced by this graft were compared with those of a control device. Both types of grafts were connected with vessel mimic and positioned in ultrasound flow phantoms with identical geometry. Constant flow rates were applied. Data collected in the cross-sectional view distal from the graft outflow and dual-beam vector Doppler was applied to create 2-D velocity maps. A single-spiral flow pattern was found for the flow-modified graft, and double or triple spirals for the control graft. In-plane maximum velocity was greater for the flow-modified graft than for the control device.
    Original languageEnglish
    Pages (from-to)2295-2307
    Number of pages13
    JournalUltrasound in Medicine and Biology
    Issue number12
    Publication statusPublished - 2013


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