Prosthetic grafts are used for the treatment of peripheral arterial disease. Re-stenosis in the distal anastomosis of these grafts is a common reason for graft occlusion. The role of local hemodynamics in development of neo-intimal hyperplasia is well known. A new graft design has been proposed for the induction of optimized spiral flow in the host vessel. The secondary flow motions induced by this graft were compared with those of a control device. Both types of grafts were connected with vessel mimic and positioned in ultrasound flow phantoms with identical geometry. Constant flow rates were applied. Data collected in the cross-sectional view distal from the graft outflow and dual-beam vector Doppler was applied to create 2-D velocity maps. A single-spiral flow pattern was found for the flow-modified graft, and double or triple spirals for the control graft. In-plane maximum velocity was greater for the flow-modified graft than for the control device.
|Number of pages||13|
|Journal||Ultrasound in Medicine and Biology|
|Publication status||Published - 2013|
FingerprintDive into the research topics of 'Secondary flow in peripheral vascular prosthetic grafts using vector Doppler imaging'. Together they form a unique fingerprint.
Fluid Dynamic Assessments of Spiral Flow Induced by Vascular GraftsAuthor: Kokkalis, E., 2014
Supervisor: Houston, J. (Supervisor), Corner, G. (Supervisor) & Hoskins, P. R. (External person) (Supervisor)
Student thesis: Doctoral Thesis › Doctor of PhilosophyFile