Separation of two phosphorylase kinase phosphatase activities in rabbit skeletal muscle

J. F. Antoniw, P. Cohen

    Research output: Contribution to journalArticle

    4 Citations (Scopus)

    Abstract

    β Phosphorylase kinase phosphatase is the enzyme which reverses hormonal activation of phosphorylase kinase. The expression of its activity is dependent on the state of phosphorylation of the α subunit. α Phosphorylase kinase phosphatase can therefore be regarded as the enzyme which inhibits the reversal of the hormonal activation of phosphorylase kinase. The presence of separate enzymes in skeletal muscle specific for the dephosphorylation of each site implies that additional control mechanisms may well operate and the reversal of hormone stimulation may be under a very sophisticated form of control.

    Original languageEnglish
    Pages (from-to)83-84
    Number of pages2
    JournalBiochemical Society Transactions
    Volume3
    Issue number1
    DOIs
    Publication statusPublished - 1 Feb 1975

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    Phosphorylase Kinase
    Muscle
    Skeletal Muscle
    Rabbits
    Enzymes
    Chemical activation
    Phosphorylation
    Hormones
    phosphorylase kinase phosphatase

    Cite this

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    Separation of two phosphorylase kinase phosphatase activities in rabbit skeletal muscle. / Antoniw, J. F.; Cohen, P.

    In: Biochemical Society Transactions, Vol. 3, No. 1, 01.02.1975, p. 83-84.

    Research output: Contribution to journalArticle

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