Serine-threonine kinases in TCR signaling

María N. Navarro; Doreen A. Cantrell

doi:10.1038/ni.2941

Serine-threonine kinases in TCR signaling

María N. Navarro, Doreen A. Cantrell (Lead / Corresponding author)

Research output: Contribution to journal › Article › peer-review

54 Citations (Scopus)

Abstract

T lymphocyte proliferation and differentiation are controlled by signaling pathways initiated by the T cell antigen receptor. Here we explore how key serine-threonine kinases and their substrates mediate T cell signaling and coordinate T cell metabolism to meet the metabolic demands of participating in an immune response.

Original language	English
Pages (from-to)	808-814
Number of pages	7
Journal	Nature Immunology
Volume	15
Issue number	9
DOIs	https://doi.org/10.1038/ni.2941
Publication status	Published - Sept 2014

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10.1038/ni.2941

http://www.nature.com/ni/journal/v15/n9/index.html

1 Finished
1 Active

Serine Kinase Pathways that Determine T Lymphocyte Activation and Cell Fate Choices (Principal Research Fellowship renewal)
Cantrell, D.
Wellcome Trust
1/10/12 → 1/10/24
Project: Research
How Does O-GlcNAc Transferase Integrate Glucose and Glutamine Metabolism to Control Cytotoxic T Lymphocyte Function?
Cantrell, D.
Wellcome Trust
1/01/16 → 30/06/17
Project: Research

Cite this

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title = "Serine-threonine kinases in TCR signaling",

abstract = "T lymphocyte proliferation and differentiation are controlled by signaling pathways initiated by the T cell antigen receptor. Here we explore how key serine-threonine kinases and their substrates mediate T cell signaling and coordinate T cell metabolism to meet the metabolic demands of participating in an immune response.",

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Serine-threonine kinases in TCR signaling

Abstract

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Serine Kinase Pathways that Determine T Lymphocyte Activation and Cell Fate Choices (Principal Research Fellowship renewal)

How Does O-GlcNAc Transferase Integrate Glucose and Glutamine Metabolism to Control Cytotoxic T Lymphocyte Function?

Cite this