Session 3: Intra-operative radiotherapy – creating new surgical boundaries

A. Patel (Lead / Corresponding author), G. Chang, A. Wale, I. Chong, H. Rutten, J. Nicholls, M. Hawkins, R. J.C. Steele, J. Marks, G. Brown

Research output: Contribution to journalArticle


In patients with advanced and recurrent colorectal cancer, surgical resection with clear margins is the greatest challenge and is limited by known anatomical constraints. Preoperative or intra-operative assessment of the limits of surgical dissection may help to explore the possibility of improving resectability through either targeted external beam radiotherapy or intra-operative radiotherapy. Professor Chang reviews the evidence base and potential advantages and disadvantages of this approach, whilst the expert panel agree a consensus on the evidence for assessment and therapy of such patients.

Original languageEnglish
Article number15
Pages (from-to)65-75
Number of pages11
JournalColorectal Disease
Issue numberSupp. 1
Early online date24 May 2018
Publication statusPublished - 24 May 2018

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    Patel, A., Chang, G., Wale, A., Chong, I., Rutten, H., Nicholls, J., Hawkins, M., Steele, R. J. C., Marks, J., & Brown, G. (2018). Session 3: Intra-operative radiotherapy – creating new surgical boundaries. Colorectal Disease, 20(Supp. 1), 65-75. [15].