Sex steroids, growth factors and mammographic density: a cross-sectional study of UK postmenopausal Caucasian and Afro-Caribbean women

Valerie A McCormack, Mitch Dowsett, Elizabeth Folkerd, Nichola Johnson, Claire Palles, Ben Coupland, Jeff M Holly, Sarah J Vinnicombe, Nicholas M Perry, Isabel dos Santos Silva

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    41 Citations (Scopus)

    Abstract

    Sex steroids, insulin-like growth factors (IGFs) and prolactin are breast cancer risk factors but whether their effects are mediated through mammographic density, one of the strongest risk factors for breast cancer, is unknown. If such a hormonal basis of mammographic density exists, hormones may underlie ethnic differences in both mammographic density and breast cancer incidence rates.
    Original languageEnglish
    Pages (from-to)R38
    Number of pages10
    JournalBreast Cancer Research
    Volume11
    Issue number3
    DOIs
    Publication statusPublished - 2009

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