Sex steroids, growth factors and mammographic density: a cross-sectional study of UK postmenopausal Caucasian and Afro-Caribbean women

Valerie A McCormack; Mitch Dowsett; Elizabeth Folkerd; Nichola Johnson; Claire Palles; Ben Coupland; Jeff M Holly; Sarah J Vinnicombe; Nicholas M Perry; Isabel dos Santos Silva

doi:10.1186/bcr2325

Sex steroids, growth factors and mammographic density: a cross-sectional study of UK postmenopausal Caucasian and Afro-Caribbean women

Valerie A McCormack (Lead / Corresponding author), Mitch Dowsett, Elizabeth Folkerd, Nichola Johnson, Claire Palles, Ben Coupland, Jeff M Holly, Sarah J Vinnicombe, Nicholas M Perry, Isabel dos Santos Silva

Research output: Contribution to journal › Article › peer-review

42 Citations (Scopus)

Abstract

Sex steroids, insulin-like growth factors (IGFs) and prolactin are breast cancer risk factors but whether their effects are mediated through mammographic density, one of the strongest risk factors for breast cancer, is unknown. If such a hormonal basis of mammographic density exists, hormones may underlie ethnic differences in both mammographic density and breast cancer incidence rates.

Original language	English
Pages (from-to)	R38
Number of pages	10
Journal	Breast Cancer Research
Volume	11
Issue number	3
DOIs	https://doi.org/10.1186/bcr2325
Publication status	Published - 2009

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10.1186/bcr2325

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abstract = "Sex steroids, insulin-like growth factors (IGFs) and prolactin are breast cancer risk factors but whether their effects are mediated through mammographic density, one of the strongest risk factors for breast cancer, is unknown. If such a hormonal basis of mammographic density exists, hormones may underlie ethnic differences in both mammographic density and breast cancer incidence rates.",

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AU - McCormack, Valerie A

AU - Dowsett, Mitch

AU - Folkerd, Elizabeth

AU - Johnson, Nichola

AU - Palles, Claire

AU - Coupland, Ben

AU - Holly, Jeff M

AU - Vinnicombe, Sarah J

AU - Perry, Nicholas M

AU - dos Santos Silva, Isabel

PY - 2009

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AB - Sex steroids, insulin-like growth factors (IGFs) and prolactin are breast cancer risk factors but whether their effects are mediated through mammographic density, one of the strongest risk factors for breast cancer, is unknown. If such a hormonal basis of mammographic density exists, hormones may underlie ethnic differences in both mammographic density and breast cancer incidence rates.

U2 - 10.1186/bcr2325

DO - 10.1186/bcr2325

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JO - Breast Cancer Research

JF - Breast Cancer Research

IS - 3

ER -

Sex steroids, growth factors and mammographic density: a cross-sectional study of UK postmenopausal Caucasian and Afro-Caribbean women

Abstract

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