Should we wait or not?: The preferable option for patients with stage IV oral cancer in COVID-19 pandemic

Atanu Bhattacharjee; Vijay M Patil; Rajesh Dikshit; Kumar Prabhash; Arjun Singh; Pankaj Chaturvedi

doi:10.1002/hed.26196

Should we wait or not? The preferable option for patients with stage IV oral cancer in COVID-19 pandemic

Atanu Bhattacharjee
, Vijay M Patil
, Rajesh Dikshit
, Kumar Prabhash
, Arjun Singh
, Pankaj Chaturvedi (Lead / Corresponding author)

Population Health and Genomics

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Background
The coronavirus infection is rapidly spreading, putting a strain on health care services across the globe. Patients with oral cancer are susceptible often immunosuppressed due to the disease and/or the treatment received.
Methods
We performed a simulation of the currently available data using a multistate and hazards model to provide an objective model for counseling and decision making for health care workers.
Results
Stage IV patients with oral cancer who did not receive treatment had progression of disease and an increased mortality rate compared to patients who receive treatment but did not contract COVID-19. The patients who received treatment and got affected with COVID-19 had a far worse impact and higher mortality rate than all other groups.
Conclusion
Isolation and deferring treatment for stage IV patients with oral cancer, so as to avoid hospital visits and contraction of COVID-19, is an advisable strategy based on this model.

Original language	English
Pages (from-to)	1173-1178
Number of pages	6
Journal	Head & Neck
Volume	42
Issue number	6
Early online date	28 Apr 2020
DOIs	https://doi.org/10.1002/hed.26196
Publication status	Published - 27 May 2020

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

cancer
coronavirus
COVID-19
simulation

Access to Document

10.1002/hed.26196

Cite this

@article{2ec1d78a1908472cad4c449e865aa6df,

title = "Should we wait or not?: The preferable option for patients with stage IV oral cancer in COVID-19 pandemic",

abstract = "Background The coronavirus infection is rapidly spreading, putting a strain on health care services across the globe. Patients with oral cancer are susceptible often immunosuppressed due to the disease and/or the treatment received. Methods We performed a simulation of the currently available data using a multistate and hazards model to provide an objective model for counseling and decision making for health care workers. Results Stage IV patients with oral cancer who did not receive treatment had progression of disease and an increased mortality rate compared to patients who receive treatment but did not contract COVID-19. The patients who received treatment and got affected with COVID-19 had a far worse impact and higher mortality rate than all other groups. Conclusion Isolation and deferring treatment for stage IV patients with oral cancer, so as to avoid hospital visits and contraction of COVID-19, is an advisable strategy based on this model.",

keywords = "cancer, coronavirus, COVID-19, simulation",

author = "Atanu Bhattacharjee and Patil, \{Vijay M\} and Rajesh Dikshit and Kumar Prabhash and Arjun Singh and Pankaj Chaturvedi",

note = " {\textcopyright} 2020 Wiley Periodicals, Inc.",

year = "2020",

month = may,

day = "27",

doi = "10.1002/hed.26196",

language = "English",

volume = "42",

pages = "1173--1178",

journal = "Head \& Neck",

issn = "1097-0347",

publisher = "Wiley",

number = "6",

}

TY - JOUR

T1 - Should we wait or not?

T2 - The preferable option for patients with stage IV oral cancer in COVID-19 pandemic

AU - Bhattacharjee, Atanu

AU - Patil, Vijay M

AU - Dikshit, Rajesh

AU - Prabhash, Kumar

AU - Singh, Arjun

AU - Chaturvedi, Pankaj

PY - 2020/5/27

Y1 - 2020/5/27

N2 - Background The coronavirus infection is rapidly spreading, putting a strain on health care services across the globe. Patients with oral cancer are susceptible often immunosuppressed due to the disease and/or the treatment received. Methods We performed a simulation of the currently available data using a multistate and hazards model to provide an objective model for counseling and decision making for health care workers. Results Stage IV patients with oral cancer who did not receive treatment had progression of disease and an increased mortality rate compared to patients who receive treatment but did not contract COVID-19. The patients who received treatment and got affected with COVID-19 had a far worse impact and higher mortality rate than all other groups. Conclusion Isolation and deferring treatment for stage IV patients with oral cancer, so as to avoid hospital visits and contraction of COVID-19, is an advisable strategy based on this model.

AB - Background The coronavirus infection is rapidly spreading, putting a strain on health care services across the globe. Patients with oral cancer are susceptible often immunosuppressed due to the disease and/or the treatment received. Methods We performed a simulation of the currently available data using a multistate and hazards model to provide an objective model for counseling and decision making for health care workers. Results Stage IV patients with oral cancer who did not receive treatment had progression of disease and an increased mortality rate compared to patients who receive treatment but did not contract COVID-19. The patients who received treatment and got affected with COVID-19 had a far worse impact and higher mortality rate than all other groups. Conclusion Isolation and deferring treatment for stage IV patients with oral cancer, so as to avoid hospital visits and contraction of COVID-19, is an advisable strategy based on this model.

KW - cancer

KW - coronavirus

KW - COVID-19

KW - simulation

UR - https://www.scopus.com/record/display.uri?eid=2-s2.0-85084008942&origin=resultslist&sort=plf-f&src=s&sid=f652cc40d54ae51fa205bef60454584a&sot=b&sdt=b&s=TITLE-ABS-KEY%28Should+we+wait+or+not%3F+The+preferable+option+for+patients+with+stage+IV+oral+cancer+in+COVID-19+pandemic%29&sl=119&sessionSearchId=f652cc40d54ae51fa205bef60454584a&relpos=0

U2 - 10.1002/hed.26196

DO - 10.1002/hed.26196

M3 - Article

SN - 1097-0347

VL - 42

SP - 1173

EP - 1178

JO - Head & Neck

JF - Head & Neck

IS - 6

ER -