Simple instrument for the characterization of diffuse reflectance

TY - GEN

T1 - Simple instrument for the characterization of diffuse reflectance

AU - Giardini, Mario Ettore

AU - Loconte, Laura

AU - Gelmetti, Andrea

AU - Guizzetti, Giovanni

AU - Lago, Paolo

N1 - © (1999) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE).

PY - 1999/1/19

Y1 - 1999/1/19

N2 - An apparatus for the measurement of the radial dependence of the continuous-wave diffuse reflectance of a tissue is described. It consists in a probe, which is applied on the tissue, and a detection unit. By employing an array of incoherent semiconductor light sources (LED's) and continuous- wave detection, probe structure is considerably simpler than other devices described in literature, allowing moreover an efficient coupling of the emitted light towards the tissue. The high responsivity so obtained permits fast and accurate measurements. Measurement speed, probe compactness and accuracy are potentially sufficient for the in-vivo application of the method to surgically exposed tissue. A preliminary set of data, measured on a scattering phantom and on non-exposed in-vivo tissue, is presented. Even though available models fitted to the measured data give the correct order of magnitude for light transport coefficients, in order to extract reliable absolute values they should be corrected for probe nonidealities. The availability of extensive high- quality in-vivo data is to this regard stimulating for further theoretical investigations.

AB - An apparatus for the measurement of the radial dependence of the continuous-wave diffuse reflectance of a tissue is described. It consists in a probe, which is applied on the tissue, and a detection unit. By employing an array of incoherent semiconductor light sources (LED's) and continuous- wave detection, probe structure is considerably simpler than other devices described in literature, allowing moreover an efficient coupling of the emitted light towards the tissue. The high responsivity so obtained permits fast and accurate measurements. Measurement speed, probe compactness and accuracy are potentially sufficient for the in-vivo application of the method to surgically exposed tissue. A preliminary set of data, measured on a scattering phantom and on non-exposed in-vivo tissue, is presented. Even though available models fitted to the measured data give the correct order of magnitude for light transport coefficients, in order to extract reliable absolute values they should be corrected for probe nonidealities. The availability of extensive high- quality in-vivo data is to this regard stimulating for further theoretical investigations.

KW - Near-infrared spectroscopy

KW - NIRS

U2 - 10.1117/12.336818

DO - 10.1117/12.336818

M3 - Conference contribution

VL - 3568

T3 - Proceedings of SPIE - The International Society for Optical Engineering

SP - 59

EP - 63

BT - Optical Biopsies and Microscopic Techniques III

A2 - Bigio, Irving J.

A2 - Schneckenburger, Herbert

A2 - Slavik, Jan

A2 - Svanberg, Katarina

A2 - Viallet, Pierre M.

PB - SPIE-International Society for Optical Engineering

T2 - BIOS Europe 1998

Y2 - 8 September 1998 through 12 September 1998

ER -