Abstract
A probe-level model for analysis of GeneChip gene-expression data is presented which identified more than 10,000 single-feature polymorphisms (SFP) between two barley genotypes. The method has good sensitivity, as 67% of known single-nucleotide polymorphisms (SNP) were called as SFPs. This method is applicable to all oligonucleotide microarray data, accounts for SNP effects in gene-expression data and represents an efficient and versatile approach for highly parallel marker identification in large genomes.
Original language | English |
---|---|
Article number | R54 |
Number of pages | 10 |
Journal | Genome Biology |
Volume | 6 |
Issue number | 6 |
Early online date | 11 May 2005 |
DOIs | |
Publication status | Published - 1 Dec 2005 |
ASJC Scopus subject areas
- Ecology, Evolution, Behavior and Systematics
- Genetics
- Cell Biology