Skin wound closure with a novel shape-memory alloy fixator

Y. Ng; S. M. Shimi; N. Kernohan; T. G. Frank; P. A. Campbell; D. Martin; J. Gove; A. Cuschieri

doi:10.1007/s00464-004-0001-9

Skin wound closure with a novel shape-memory alloy fixator

Y. Ng, S. M. Shimi, N. Kernohan, T. G. Frank, P. A. Campbell, D. Martin, J. Gove, A. Cuschieri

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Background: Previously, we have described novel, thermally deployable tissue fixators based on the shape-memory properties of nickel titanium. The present study reports on the in vivo wound closure with these fixators as a preliminary to evaluating their use for bowel anastomoses. Methods: Twenty adult Sprague-Dawley rats had 2.0-cm dorsal skin incisions approximated either with shape-memory alloy (SMA) fixators or conventional skin staples on a random basis. Electrical resistance heating was used to transform and deploy the SMA fixators into the wound. The rats were killed on day 14 or day 28 and wound specimens were harvested for force distraction studies and histologic examination. Results: There was no incidence of wound dehiscence. 14- and 28-day wounds from both groups showed no significant difference in breaking force or energy. Histology revealed appropriate stages of wound healing for both SMA-closed and control wounds. Conclusions: The results confirm the efficacy and safety of tissue-edge approximation with SMA fixators. © Springer Science+Business Media, Inc. 2005.

Original language	English
Pages (from-to)	311-315
Number of pages	5
Journal	Surgical Endoscopy
Volume	20
Issue number	2
DOIs	https://doi.org/10.1007/s00464-004-0001-9
Publication status	Published - Feb 2006

Keywords

In vivo skin closure
NiTi shape-memory alloy (SMA) fixators
Wound closure

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10.1007/s00464-004-0001-9

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title = "Skin wound closure with a novel shape-memory alloy fixator",

abstract = "Background: Previously, we have described novel, thermally deployable tissue fixators based on the shape-memory properties of nickel titanium. The present study reports on the in vivo wound closure with these fixators as a preliminary to evaluating their use for bowel anastomoses. Methods: Twenty adult Sprague-Dawley rats had 2.0-cm dorsal skin incisions approximated either with shape-memory alloy (SMA) fixators or conventional skin staples on a random basis. Electrical resistance heating was used to transform and deploy the SMA fixators into the wound. The rats were killed on day 14 or day 28 and wound specimens were harvested for force distraction studies and histologic examination. Results: There was no incidence of wound dehiscence. 14- and 28-day wounds from both groups showed no significant difference in breaking force or energy. Histology revealed appropriate stages of wound healing for both SMA-closed and control wounds. Conclusions: The results confirm the efficacy and safety of tissue-edge approximation with SMA fixators. {\textcopyright} Springer Science+Business Media, Inc. 2005.",

keywords = "In vivo skin closure, NiTi shape-memory alloy (SMA) fixators, Wound closure",

author = "Y. Ng and Shimi, {S. M.} and N. Kernohan and Frank, {T. G.} and Campbell, {P. A.} and D. Martin and J. Gove and A. Cuschieri",

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year = "2006",

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doi = "10.1007/s00464-004-0001-9",

language = "English",

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T1 - Skin wound closure with a novel shape-memory alloy fixator

AU - Ng, Y.

AU - Shimi, S. M.

AU - Kernohan, N.

AU - Frank, T. G.

AU - Campbell, P. A.

AU - Martin, D.

AU - Gove, J.

AU - Cuschieri, A.

N1 - dc.publisher: Springer Verlag dc.description.sponsorship: Wellcome Trust Grant 057735

PY - 2006/2

Y1 - 2006/2

N2 - Background: Previously, we have described novel, thermally deployable tissue fixators based on the shape-memory properties of nickel titanium. The present study reports on the in vivo wound closure with these fixators as a preliminary to evaluating their use for bowel anastomoses. Methods: Twenty adult Sprague-Dawley rats had 2.0-cm dorsal skin incisions approximated either with shape-memory alloy (SMA) fixators or conventional skin staples on a random basis. Electrical resistance heating was used to transform and deploy the SMA fixators into the wound. The rats were killed on day 14 or day 28 and wound specimens were harvested for force distraction studies and histologic examination. Results: There was no incidence of wound dehiscence. 14- and 28-day wounds from both groups showed no significant difference in breaking force or energy. Histology revealed appropriate stages of wound healing for both SMA-closed and control wounds. Conclusions: The results confirm the efficacy and safety of tissue-edge approximation with SMA fixators. © Springer Science+Business Media, Inc. 2005.

AB - Background: Previously, we have described novel, thermally deployable tissue fixators based on the shape-memory properties of nickel titanium. The present study reports on the in vivo wound closure with these fixators as a preliminary to evaluating their use for bowel anastomoses. Methods: Twenty adult Sprague-Dawley rats had 2.0-cm dorsal skin incisions approximated either with shape-memory alloy (SMA) fixators or conventional skin staples on a random basis. Electrical resistance heating was used to transform and deploy the SMA fixators into the wound. The rats were killed on day 14 or day 28 and wound specimens were harvested for force distraction studies and histologic examination. Results: There was no incidence of wound dehiscence. 14- and 28-day wounds from both groups showed no significant difference in breaking force or energy. Histology revealed appropriate stages of wound healing for both SMA-closed and control wounds. Conclusions: The results confirm the efficacy and safety of tissue-edge approximation with SMA fixators. © Springer Science+Business Media, Inc. 2005.

KW - In vivo skin closure

KW - NiTi shape-memory alloy (SMA) fixators

KW - Wound closure

U2 - 10.1007/s00464-004-0001-9

DO - 10.1007/s00464-004-0001-9

M3 - Article

C2 - 16362482

SN - 0930-2794

VL - 20

SP - 311

EP - 315

JO - Surgical Endoscopy

JF - Surgical Endoscopy

IS - 2

ER -

Skin wound closure with a novel shape-memory alloy fixator

Abstract

Keywords

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