Abstract
Compounds having the general structure A - L - B are presented wherein A and B are independently an E3 ubiquitin ligase protein binding ligand compound of formula 1A or 1 B. Pharmaceutical compositions comprising these compounds and methods of use are also presented.
Original language | English |
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Patent number | WO/2018/189554 |
IPC | C07D 417/14 2006.1, C07K 5/062 2006.1,A61P 35/00 2006.1,A61K 38/05 2006.1 |
Priority date | 14/04/17 |
Filing date | 13/04/18 |
Publication status | Published - 18 Oct 2018 |