Small molecules

Alessio Ciulli; Chiara Maniaci; Scott Hughes; Andrea Testa

Small molecules

Alessio Ciulli (Inventor)
, Chiara Maniaci (Inventor)
, Scott Hughes (Inventor)
, Andrea Testa (Inventor)

Biological Chemistry and Drug Discovery

Research output: Patent

Abstract

Compounds having the general structure A - L - B are presented wherein A and B are independently an E3 ubiquitin ligase protein binding ligand compound of formula 1A or 1 B. Pharmaceutical compositions comprising these compounds and methods of use are also presented.

Original language	English
Patent number	WO/2018/189554
IPC	C07D 417/14 2006.1, C07K 5/062 2006.1,A61P 35/00 2006.1,A61K 38/05 2006.1
Priority date	14/04/17
Filing date	13/04/18
Publication status	Published - 18 Oct 2018

Cite this

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title = "Small molecules",

abstract = "Compounds having the general structure A - L - B are presented wherein A and B are independently an E3 ubiquitin ligase protein binding ligand compound of formula 1A or 1 B. Pharmaceutical compositions comprising these compounds and methods of use are also presented.",

author = "Alessio Ciulli and Chiara Maniaci and Scott Hughes and Andrea Testa",

year = "2018",

month = oct,

day = "18",

language = "English",

type = "Patent",

note = "WO/2018/189554; C07D 417/14 2006.1, C07K 5/062 2006.1,A61P 35/00 2006.1,A61K 38/05 2006.1",

}

TY - PAT

T1 - Small molecules

AU - Ciulli, Alessio

AU - Maniaci, Chiara

AU - Hughes, Scott

AU - Testa, Andrea

PY - 2018/10/18

Y1 - 2018/10/18

N2 - Compounds having the general structure A - L - B are presented wherein A and B are independently an E3 ubiquitin ligase protein binding ligand compound of formula 1A or 1 B. Pharmaceutical compositions comprising these compounds and methods of use are also presented.

AB - Compounds having the general structure A - L - B are presented wherein A and B are independently an E3 ubiquitin ligase protein binding ligand compound of formula 1A or 1 B. Pharmaceutical compositions comprising these compounds and methods of use are also presented.

UR - https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2018189554

M3 - Patent

M1 - WO/2018/189554

Y2 - 2018/04/13

ER -

Small molecules

Abstract

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