Some principles and practices of genetic biobanking studies

A. K. MacLeod, D. C. M. Liewald, M. M. McGilchrist, A. D. Morris, S. M. Kerr, D. J. Porteous

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    11 Citations (Scopus)

    Abstract

    Genetic biobanking studies are becoming increasingly common as researchers recognise the need for large samples to identify the genetic basis of susceptibility to complex disease. In the present review, the authors give a brief overview of some of the issues that should be considered when implementing such a large-scale project, from study design to sample management, data coding and storage to the statistical analysis and engagement with the public. Specific solutions to these issues are presented, as implemented in the Generation Scotland projects, but the general principles outlined are relevant to any biobanking study.

    Original languageEnglish
    Pages (from-to)419-425
    Number of pages7
    JournalEuropean Respiratory Journal
    Volume33
    Issue number2
    DOIs
    Publication statusPublished - Feb 2009

    Keywords

    • Biobanking
    • data acquisition
    • data coding
    • laboratory information management system
    • statistical genetics
    • OBSTRUCTIVE SLEEP-APNEA
    • ASSOCIATION

    Cite this

    MacLeod, A. K., Liewald, D. C. M., McGilchrist, M. M., Morris, A. D., Kerr, S. M., & Porteous, D. J. (2009). Some principles and practices of genetic biobanking studies. European Respiratory Journal, 33(2), 419-425. https://doi.org/10.1183/09031936.00043508