Somitogenesis

Miguel Maroto; Robert A. Bone; J. Kim Dale

doi:10.1242/dev.069310

Somitogenesis

Miguel Maroto, Robert A. Bone, J. Kim Dale

Research output: Contribution to journal › Article › peer-review

77 Citations (Scopus)

Abstract

A segmented body plan is fundamental to all vertebrate species and this bestows both rigidity and flexibility on the body. Segmentation is initiated through the process of somitogenesis. This article aims to provide a broad and balanced cross-species overview of somitogenesis and to highlight the key molecular and cellular events involved in each stage of segmentation. We highlight where our understanding of this multifaceted process relies on strong experimental evidence as well as those aspects where our understanding still relies largely on models.

Original language	English
Pages (from-to)	2453-2456
Number of pages	4
Journal	Development
Volume	139
Issue number	14
DOIs	https://doi.org/10.1242/dev.069310
Publication status	Published - 2012

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10.1242/dev.069310

Aref#d: 21932. The Interplay of Wnt and Notch Signalling in the Segmentation Clock Mechanism
Dale, K. (Investigator)
23/11/09 → 22/11/13
Project: Research

Cite this

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title = "Somitogenesis",

abstract = "A segmented body plan is fundamental to all vertebrate species and this bestows both rigidity and flexibility on the body. Segmentation is initiated through the process of somitogenesis. This article aims to provide a broad and balanced cross-species overview of somitogenesis and to highlight the key molecular and cellular events involved in each stage of segmentation. We highlight where our understanding of this multifaceted process relies on strong experimental evidence as well as those aspects where our understanding still relies largely on models.",

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AU - Bone, Robert A.

AU - Dale, J. Kim

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AB - A segmented body plan is fundamental to all vertebrate species and this bestows both rigidity and flexibility on the body. Segmentation is initiated through the process of somitogenesis. This article aims to provide a broad and balanced cross-species overview of somitogenesis and to highlight the key molecular and cellular events involved in each stage of segmentation. We highlight where our understanding of this multifaceted process relies on strong experimental evidence as well as those aspects where our understanding still relies largely on models.

U2 - 10.1242/dev.069310

DO - 10.1242/dev.069310

M3 - Article

C2 - 22736241

SN - 0950-1991

VL - 139

SP - 2453

EP - 2456

JO - Development

JF - Development

IS - 14

ER -

Somitogenesis

Abstract

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Aref#d: 21932. The Interplay of Wnt and Notch Signalling in the Segmentation Clock Mechanism

Cite this