Abstract
A method of selectively inhibiting a bromodomain in the presence of other bromodomains comprising introducing a functionally silent mutation into the bromodomain in the presence of other wild type bromodomains and selectively inhibiting the mutated bromodomain.
Translated title of the contribution | Enzymes functional probes |
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Original language | French |
Patent number | WO/2015/079259 |
Priority date | 28/11/13 |
Filing date | 28/11/14 |
Publication status | Published - 4 Jun 2015 |