Specificity and mechanism of Acinetobacter baumanii nicotinamidase: implications for activation of the front-line tuberculosis drug pyrazinamide

Paul K. Fyfe; Vincenzo A. Rao; Aleksandra Zemla; Scott Cameron; William N. Hunter

doi:10.1002/anie.200903407

Specificity and mechanism of Acinetobacter baumanii nicotinamidase: implications for activation of the front-line tuberculosis drug pyrazinamide

Paul K. Fyfe, Vincenzo A. Rao, Aleksandra Zemla, Scott Cameron, William N. Hunter (Lead / Corresponding author)

Research output: Contribution to journal › Article

Original language	English
Pages (from-to)	9176-9179
Number of pages	4
Journal	Angewandte Chemie International Edition
Volume	48
Issue number	48
DOIs	https://doi.org/10.1002/anie.200903407
Publication status	Published - 2009

Keywords

drug discovery
enzymes
mechanisms
tuberculosis
zinc
MYCOBACTERIUM-TUBERCULOSIS
CRYSTAL-STRUCTURE

Access to Document

10.1002/anie.200903407

Link to publication in Scopus

Cite this

Fyfe, P. K., Rao, V. A., Zemla, A., Cameron, S., & Hunter, W. N. (2009). Specificity and mechanism of Acinetobacter baumanii nicotinamidase: implications for activation of the front-line tuberculosis drug pyrazinamide. Angewandte Chemie International Edition, 48(48), 9176-9179. https://doi.org/10.1002/anie.200903407

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Specificity and mechanism of Acinetobacter baumanii nicotinamidase : implications for activation of the front-line tuberculosis drug pyrazinamide. / Fyfe, Paul K.; Rao, Vincenzo A.; Zemla, Aleksandra; Cameron, Scott; Hunter, William N. (Lead / Corresponding author).

In: Angewandte Chemie International Edition, Vol. 48, No. 48, 2009, p. 9176-9179.

Research output: Contribution to journal › Article

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