Sperm cryopreservation for impaired spermatogenesis

George Hughes, Sarah Martins da Silva (Lead / Corresponding author)

    Research output: Contribution to journalReview articlepeer-review

    2 Citations (Scopus)
    115 Downloads (Pure)

    Abstract

    Sperm cryopreservation for men with severely impaired spermatogenesis is one of the commonest reasons for short-term sperm storage, usually in advance of fertility treatment. Cryopreservation is generally very effective, although not all spermatozoa survive the process of freezing and thawing. This review considers various aspects of freezing sperm, including an overview of methods, appropriate use of cryoprotectants and practical considerations, as well as oxidative stress and mechanisms of cell cryodamage.

    Original languageEnglish
    Article numbere220106
    Number of pages11
    JournalReproduction & Fertility
    Volume4
    Issue number1
    Early online date18 Jan 2023
    DOIs
    Publication statusPublished - Jan 2023

    Keywords

    • ICSI
    • cryostorage
    • male infertility
    • sperm
    • spermatogenesis

    ASJC Scopus subject areas

    • Urology
    • Obstetrics and Gynaecology
    • Embryology
    • Reproductive Medicine

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