Sperm transport in the human female reproductive tract--a dynamic interaction

C L Barratt (Lead / Corresponding author), I D Cooke

Research output: Contribution to journalReview articlepeer-review

71 Citations (Scopus)


The interaction between sperm and the human female tract has been largely ignored. This review summarizes the data available from animal species with specific reference to sperm in the oviduct. Our knowledge of sperm transport within the human female tract is explored and, using the data available from animal species, three lines of future experimental design are suggested. Firstly, there is the need to improve and develop techniques to recover sperm successfully from the tract. Second, an in-vitro approach which examines the modulation of reproductive tract fluids on sperm function is advocated. Third, an in-vitro tissue/cell culture system is required to investigate in more detail the interaction between the epithelium and sperm. Using such approaches many of the questions posed in this review can be addressed confidently in the near future.

Original languageEnglish
Pages (from-to)394-411
Number of pages18
JournalInternational Journal of Andrology
Issue number6
Publication statusPublished - Dec 1991


  • Animals
  • Fallopian Tubes/physiology
  • Humans
  • Male
  • Sperm Capacitation
  • Sperm Motility


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