Sperm-zona interaction and recombinant DNA technology

Neil R. Chapman, Christopher L.R. Barratt (Lead / Corresponding author)

Research output: Contribution to journalReview articlepeer-review

6 Citations (Scopus)


Recombinant DNA technology has revolutionized our understanding of many biological systems. However, such techniques and their application have not been fully exploited in the study of sperm zona interaction. Using examples from other biological systems, we ourline several experimental approaches that are likely to significantly enhance our understanding of the gamete recognition process.

Original languageEnglish
Pages (from-to)646-650
Number of pages5
JournalMolecular Human Reproduction
Issue number8
Publication statusPublished - Aug 1997


  • Animals
  • Cloning, Organism
  • Contraception
  • DNA, Recombinant
  • Egg Proteins/biosynthesis
  • Female
  • Humans
  • Male
  • Mammals
  • Membrane Glycoproteins/biosynthesis
  • Plasmids
  • Receptors, Cell Surface/biosynthesis
  • Saccharomyces cerevisiae
  • Sperm-Ovum Interactions
  • Spermatozoa/physiology
  • Zona Pellucida/physiology
  • Zona Pellucida Glycoproteins


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