Status of neurosurgery for mental disorder in Scotland: Selective literature review and overview of current clinical activity

Keith Matthews, Muftah S. Eljamel

    Research output: Contribution to journalArticlepeer-review

    34 Citations (Scopus)

    Abstract

    Background: Despite the application of ablative neurosurgical treatments for intractable mental disorder throughout most of the past century, unequivocal evidence for efficacy has not been provided. Aims: To review the status of ablative neurosurgery for mental disorder and to describe the activities of the Scottish national service. Method: Relevant literature is reviewed alongside a description of recent clinical activity. Results: Neurosurgical treatment is offered to a small number of patients severely disabled by otherwise intractable mental disorder. There are inequalities in the strength of evidence to support the use of some of these procedures. The frequency and severity of adverse effects remains unclear. We are collecting data that should inform future practice. Conclusions: Modern neurosurgery can offer clinically meaningful symptom relief and improved function for 'untreatable' patients with chronic, severe depression and obsessive - compulsive disorder. However, follow-up studies of greater rigour are required. The potential role of non-ablative alternatives remains unclear.
    Original languageEnglish
    Pages (from-to)404-411
    Number of pages8
    JournalBritish Journal of Psychiatry
    Volume182
    DOIs
    Publication statusPublished - May 2003

    Keywords

    • Brain
    • Depressive Disorder
    • Female
    • Humans
    • Male
    • Mental Disorders
    • Mental Health Services
    • Neurosurgical Procedures
    • Obsessive-Compulsive Disorder
    • Patient Selection
    • Scotland
    • Stereotaxic Techniques
    • Treatment Outcome

    Fingerprint Dive into the research topics of 'Status of neurosurgery for mental disorder in Scotland: Selective literature review and overview of current clinical activity'. Together they form a unique fingerprint.

    Cite this