Abstract
Summary: Postoperative acute kidney injury (AKI) is a common complication of surgery that is associated with significant adverse outcomes, including increased morbidity and mortality. The perioperative burden of AKI risk factors is complex and potentially large, including high-risk nephrotoxic medications, hypotension, hypovolemia, radiologic contrast, anemia, and surgery-specific factors. Understanding the pathogenesis, risk factors, and potential cumulative impact of perioperative nephrotoxic exposures is particularly important in the prevention and reduction of perioperative AKI. This review outlines the possible strategies to reduce perioperative nephrotoxicity and the development of postoperative AKI.
| Original language | English |
|---|---|
| Pages (from-to) | 442-453 |
| Number of pages | 12 |
| Journal | Seminars in Nephrology |
| Volume | 39 |
| Issue number | 5 |
| Early online date | 9 Sept 2019 |
| DOIs | |
| Publication status | Published - Sept 2019 |
Keywords
- Perioperative
- acute kidney injury
- nephrotoxicity
- surgery
ASJC Scopus subject areas
- Nephrology
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