Stroke prediction and stroke prevention with atorvastatin in the Collaborative Atorvastatin Diabetes Study (CARDS)

TY - JOUR

T1 - Stroke prediction and stroke prevention with atorvastatin in the Collaborative Atorvastatin Diabetes Study (CARDS)

AU - Hitman, G A

AU - Colhoun, H

AU - Newman, C

AU - Szarek, M

AU - Betteridge, D J

AU - Durrington, P N

AU - Fuller, J

AU - Livingstone, S

AU - Neil, H A W

AU - CARDS Investigators

PY - 2007

Y1 - 2007

N2 - Patients with Type 2 diabetes have an elevated risk of stroke. The role of lipid levels and diabetes-specific factors in risk prediction of stroke is unclear, and estimates of efficacy of lipid-lowering therapy vary between trials. We examined predictors of stroke and the effect of atorvastatin on specific stroke subtypes in Type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS) [a trial of 2838 participants with mean low-density lipoprotein cholesterol <4.14 mmol/l, no history of macrovascular disease and randomized to atorvastatin 10 mg daily or placebo].

AB - Patients with Type 2 diabetes have an elevated risk of stroke. The role of lipid levels and diabetes-specific factors in risk prediction of stroke is unclear, and estimates of efficacy of lipid-lowering therapy vary between trials. We examined predictors of stroke and the effect of atorvastatin on specific stroke subtypes in Type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS) [a trial of 2838 participants with mean low-density lipoprotein cholesterol <4.14 mmol/l, no history of macrovascular disease and randomized to atorvastatin 10 mg daily or placebo].

U2 - 10.1111/j.1464-5491.2007.02268.x

DO - 10.1111/j.1464-5491.2007.02268.x

M3 - Article

C2 - 17894827

SN - 0742-3071

VL - 24

SP - 1313

EP - 1321

JO - Diabetic Medicine

JF - Diabetic Medicine

IS - 12

ER -