Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains

  • Jinhua Wang
  • , Tatiana Erazo
  • , Fleur M. Ferguson
  • , Dennis L. Buckley
  • , Nestor Gomez
  • , Pau Muñoz-Guardiola
  • , Nora Diéguez-Martínez
  • , Xianming Deng
  • , Mingfeng Hao
  • , Walter Massefski
  • , Oleg Fedorov
  • , Nana Kwaku Offei-Addo
  • , Paul M. Park
  • , Lingling Dai
  • , Amy DiBona
  • , Kelly Becht
  • , Nam Doo Kim
  • , Michael R. McKeown
  • , Justin M. Roberts
  • , Jinwei Zhang
  • Taebo Sim, Dario R. Alessi, James E. Bradner, Jose M. Lizcano, Stephen C. Blacklow, Jun Qi, Xiang Xu (Lead / Corresponding author), Nathanael S. Gray (Lead / Corresponding author)

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Keyphrases

Biochemistry, Genetics and Molecular Biology

Pharmacology, Toxicology and Pharmaceutical Science