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Structural basis for the specificity of PPM1H phosphatase for Rab GTPases
Dieter Waschbüsch
, Kerryn Berndsen
,
Pawel Lis
,
Axel Knebel
,
Yuko P. Y. Lam
,
Dario R. Alessi
(Lead / Corresponding author)
, Amir R. Khan (Lead / Corresponding author)
MRC PPU
Research output
:
Contribution to journal
›
Article
›
peer-review
19
Citations (Scopus)
336
Downloads (Pure)
Overview
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Projects
(2)
Research Facilities
(1)
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Dive into the research topics of 'Structural basis for the specificity of PPM1H phosphatase for Rab GTPases'. Together they form a unique fingerprint.
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Keyphrases
Phosphatase
100%
Rab GTPase
100%
PPM1H
100%
Flap
57%
Leucine-rich Repeat Kinase 2 (LRRK2)
57%
Cellular Assay
28%
Rab8a
28%
3D Modeling
14%
Serine-threonine Kinase
14%
Chimera
14%
Parkinson's Disease
14%
Protein Phosphatase
14%
Active Sites
14%
Histone
14%
Metal-dependent
14%
Specific Interactions
14%
Highly Selective
14%
Epigenetics
14%
Dephosphorylate
14%
Molecular Determinants
14%
Interaction Domains
14%
Docking Motif
14%
Tudor Domain
14%
Biochemistry, Genetics and Molecular Biology
LRRK2
100%
Phosphatase
100%
Crystal Structure
25%
Phosphoprotein Phosphatase
25%
Phosphotransferase
25%
Kinase
25%
Cross-Link
25%
Active Site
25%
Epigenetics
25%
Epigenomics
25%
Tudor Domain
25%
Serine
25%
Threonine
25%
Histone
25%