Structural basis of PROTAC cooperative recognition for selective protein degradation

Morgan Gadd, Andrea Testa, Xavier Lucas, Kwok Ho Chan, Wenzhang Chen, Douglas Lamont, Michael Zengerle, Alessio Ciulli (Lead / Corresponding author)

Research output: Contribution to journal › Article › peer-review

817 Citations (Scopus)

673 Downloads (Pure)

3 results

Finished
Bump-BET; Bump and Hole Approach to Ellucidate Function of Individual Bromodomains of BET Proteins (Marie Curie Fellowship)
Chan, K. H. (Investigator) & Ciulli, A. (Investigator)
COMMISSION OF THE EUROPEAN COMMUNITIES
1/10/15 → 30/09/17
Project: Research
DrugE3CRL's: Probing Druggability of Multisubunit Complexes: E3 Cullin RING Ligases (ERC Starting Grant)
Ciulli, A. (Investigator)
COMMISSION OF THE EUROPEAN COMMUNITIES
1/05/13 → 30/04/18
Project: Research
A Systems Approach for the Fragment-based Development of Selective Chemical Probes of Bromodomain Function (joint with University of Oxford)
Ciulli, A. (Investigator)
Biotechnology and Biological Sciences Research Council
8/04/13 → 7/06/15
Project: Research