Structural characterization on in vitro porcine skin treated by ablative fractional laser using optical coherence tomography

Kairui Feng, Kanheng Zhou, Yuting Ling, Paul O'mahoney, Eadie Ewan, Sally H. Ibbotson, Chunhui Li, Zhihong Huang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)
163 Downloads (Pure)


Ablative fractional skin laser is widely applied for various skin conditions, especially for cosmetic repairing and promoting the located drug delivery. Although the influence of laser treatment over the skin has been explored before in means of excision and biopsy with microscopy, these approaches are invasive, only morphological and capable of distorting the skin. In this paper the authors use fresh porcine skin samples irradiated by the lasers, followed by detected by using Optical Coherence Tomography (OCT). This advanced optical technique has the ability to present the high resolution structure image of treated sample. The results shows that laser beams can produce holes left on the surface after the irradiation. The depth of holes can be affected by changes of laser energy while the diameter of holes have no corresponding relation. Plus, OCT, as a valuable imaging technology, is capable of monitoring the clinical therapy procedure and assisting the calibration.
Original languageEnglish
Title of host publicationProceedings Volume 10496
Subtitle of host publicationOptical Elastography and Tissue Biomechanics V
EditorsKirill V. Larin, David D. Sampson
PublisherSPIE-International Society for Optical Engineering
Number of pages6
ISBN (Electronic)9781510614789
ISBN (Print)9781510614772
Publication statusPublished - 19 Feb 2018
EventOptical Elastography and Tissue Biomechanics V - San Francisco, United States
Duration: 27 Jan 20181 Feb 2018

Publication series

ISSN (Print)1605-7422
ISSN (Electronic)2410-9045


ConferenceOptical Elastography and Tissue Biomechanics V
Country/TerritoryUnited States
CitySan Francisco
Internet address


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