Structural characterization on in vitro porcine skin treated by ablative fractional laser using optical coherence tomography

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Abstract

Ablative fractional skin laser is widely applied for various skin conditions, especially for cosmetic repairing and promoting the located drug delivery. Although the influence of laser treatment over the skin has been explored before in means of excision and biopsy with microscopy, these approaches are invasive, only morphological and capable of distorting the skin. In this paper the authors use fresh porcine skin samples irradiated by the lasers, followed by detected by using Optical Coherence Tomography (OCT). This advanced optical technique has the ability to present the high resolution structure image of treated sample. The results shows that laser beams can produce holes left on the surface after the irradiation. The depth of holes can be affected by changes of laser energy while the diameter of holes have no corresponding relation. Plus, OCT, as a valuable imaging technology, is capable of monitoring the clinical therapy procedure and assisting the calibration.
Original languageEnglish
Pages16
DOIs
Publication statusPublished - 19 Feb 2018
EventOptical Elastography and Tissue Biomechanics V - San Francisco, United States
Duration: 27 Jan 20181 Feb 2018
https://www.spiedigitallibrary.org/conference-proceedings-of-SPIE/10496.toc

Conference

ConferenceOptical Elastography and Tissue Biomechanics V
CountryUnited States
CitySan Francisco
Period27/01/181/02/18
Internet address

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tomography
lasers
maintenance
therapy
delivery
drugs
laser beams
microscopy
irradiation
high resolution
energy

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title = "Structural characterization on in vitro porcine skin treated by ablative fractional laser using optical coherence tomography",
abstract = "Ablative fractional skin laser is widely applied for various skin conditions, especially for cosmetic repairing and promoting the located drug delivery. Although the influence of laser treatment over the skin has been explored before in means of excision and biopsy with microscopy, these approaches are invasive, only morphological and capable of distorting the skin. In this paper the authors use fresh porcine skin samples irradiated by the lasers, followed by detected by using Optical Coherence Tomography (OCT). This advanced optical technique has the ability to present the high resolution structure image of treated sample. The results shows that laser beams can produce holes left on the surface after the irradiation. The depth of holes can be affected by changes of laser energy while the diameter of holes have no corresponding relation. Plus, OCT, as a valuable imaging technology, is capable of monitoring the clinical therapy procedure and assisting the calibration.",
author = "Kairui Feng and Kanheng Zhou and Yuting Ling and Paul O'mahoney and Eadie Ewan and Ibbotson, {Sally H.} and Chunhui Li and Zhihong Huang",
year = "2018",
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language = "English",
pages = "16",
note = "Optical Elastography and Tissue Biomechanics V ; Conference date: 27-01-2018 Through 01-02-2018",
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Structural characterization on in vitro porcine skin treated by ablative fractional laser using optical coherence tomography. / Feng, Kairui; Zhou, Kanheng; Ling, Yuting; O'mahoney, Paul; Ewan, Eadie; Ibbotson, Sally H.; Li, Chunhui; Huang, Zhihong.

2018. 16 Paper presented at Optical Elastography and Tissue Biomechanics V, San Francisco, United States.

Research output: Contribution to conferencePaper

TY - CONF

T1 - Structural characterization on in vitro porcine skin treated by ablative fractional laser using optical coherence tomography

AU - Feng, Kairui

AU - Zhou, Kanheng

AU - Ling, Yuting

AU - O'mahoney, Paul

AU - Ewan, Eadie

AU - Ibbotson, Sally H.

AU - Li, Chunhui

AU - Huang, Zhihong

PY - 2018/2/19

Y1 - 2018/2/19

N2 - Ablative fractional skin laser is widely applied for various skin conditions, especially for cosmetic repairing and promoting the located drug delivery. Although the influence of laser treatment over the skin has been explored before in means of excision and biopsy with microscopy, these approaches are invasive, only morphological and capable of distorting the skin. In this paper the authors use fresh porcine skin samples irradiated by the lasers, followed by detected by using Optical Coherence Tomography (OCT). This advanced optical technique has the ability to present the high resolution structure image of treated sample. The results shows that laser beams can produce holes left on the surface after the irradiation. The depth of holes can be affected by changes of laser energy while the diameter of holes have no corresponding relation. Plus, OCT, as a valuable imaging technology, is capable of monitoring the clinical therapy procedure and assisting the calibration.

AB - Ablative fractional skin laser is widely applied for various skin conditions, especially for cosmetic repairing and promoting the located drug delivery. Although the influence of laser treatment over the skin has been explored before in means of excision and biopsy with microscopy, these approaches are invasive, only morphological and capable of distorting the skin. In this paper the authors use fresh porcine skin samples irradiated by the lasers, followed by detected by using Optical Coherence Tomography (OCT). This advanced optical technique has the ability to present the high resolution structure image of treated sample. The results shows that laser beams can produce holes left on the surface after the irradiation. The depth of holes can be affected by changes of laser energy while the diameter of holes have no corresponding relation. Plus, OCT, as a valuable imaging technology, is capable of monitoring the clinical therapy procedure and assisting the calibration.

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