Structure and function in the nucleus

Angus I. Lamond, William C. Earnshaw

Research output: Contribution to journalReview articlepeer-review

764 Citations (Scopus)


Current evidence suggests that the nucleus has a distinct substructure, albeit one that is dynamic rather than a rigid framework. Viral infection, oncogene expression, and inherited human disorders can each cause profound and specific changes in nuclear organization. This review summarizes recent progress in understanding nuclear organization, highlighting in particular the dynamic aspects of nuclear structure.

Original languageEnglish
Pages (from-to)547-553
Number of pages7
Issue number5363
Publication statusPublished - 24 Apr 1998


Dive into the research topics of 'Structure and function in the nucleus'. Together they form a unique fingerprint.

Cite this