Structure and function in the nucleus

Angus I. Lamond, William C. Earnshaw

    Research output: Contribution to journalReview articlepeer-review

    787 Citations (Scopus)

    Abstract

    Current evidence suggests that the nucleus has a distinct substructure, albeit one that is dynamic rather than a rigid framework. Viral infection, oncogene expression, and inherited human disorders can each cause profound and specific changes in nuclear organization. This review summarizes recent progress in understanding nuclear organization, highlighting in particular the dynamic aspects of nuclear structure.

    Original languageEnglish
    Pages (from-to)547-553
    Number of pages7
    JournalScience
    Volume280
    Issue number5363
    DOIs
    Publication statusPublished - 24 Apr 1998

    ASJC Scopus subject areas

    • General

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