Structure and Function of Glutathione S-Transferases

Kenneth D. Tew; Cecil B. Pickett; Timothy J. Mantle; Bengt Mannervik; John D. Hayes

doi:10.1201/9781003760146

Structure and Function of Glutathione S-Transferases

Kenneth D. Tew
, Cecil B. Pickett
, Timothy J. Mantle
, Bengt Mannervik
, John D. Hayes

Cancer Research

Research output: Book/Report › Book

Abstract

Structure and Function of Glutathione S-Transferases provides some of the latest information available on a variety of structural and functional components of glutathione S-transferases, a family of isozymes involved in many endogenous and exogenous functions in cells. Molecular studies presented in the book focus on the regulation of these enzymes and identify important response elements. X-ray crystallographic structures show detailed information on the structural aspects of these proteins. Metabolism of a number of carcinogens and drugs is covered in detail, and the role that these enzymes play in governing drug resistance at the preclinical and clinical levels is discussed. The book will be excellent for biochemists, pharmacologists, oncologists, experimental therapeutic specialists, and others interested in glutathione S-transferases.

Original language	English
Place of Publication	Baco Raton
Publisher	CRC Press
Number of pages	336
Edition	1
ISBN (Electronic)	9781003760146, 9781040900758
DOIs	https://doi.org/10.1201/9781003760146
Publication status	Published - 2 Feb 2026

ASJC Scopus subject areas

General Medicine
General Pharmacology, Toxicology and Pharmaceutics
General Chemistry
General Biochemistry,Genetics and Molecular Biology
General Agricultural and Biological Sciences

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10.1201/9781003760146

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abstract = "Structure and Function of Glutathione S-Transferases provides some of the latest information available on a variety of structural and functional components of glutathione S-transferases, a family of isozymes involved in many endogenous and exogenous functions in cells. Molecular studies presented in the book focus on the regulation of these enzymes and identify important response elements. X-ray crystallographic structures show detailed information on the structural aspects of these proteins. Metabolism of a number of carcinogens and drugs is covered in detail, and the role that these enzymes play in governing drug resistance at the preclinical and clinical levels is discussed. The book will be excellent for biochemists, pharmacologists, oncologists, experimental therapeutic specialists, and others interested in glutathione S-transferases.",

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AU - Mannervik, Bengt

AU - Hayes, John D.

PY - 2026/2/2

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AB - Structure and Function of Glutathione S-Transferases provides some of the latest information available on a variety of structural and functional components of glutathione S-transferases, a family of isozymes involved in many endogenous and exogenous functions in cells. Molecular studies presented in the book focus on the regulation of these enzymes and identify important response elements. X-ray crystallographic structures show detailed information on the structural aspects of these proteins. Metabolism of a number of carcinogens and drugs is covered in detail, and the role that these enzymes play in governing drug resistance at the preclinical and clinical levels is discussed. The book will be excellent for biochemists, pharmacologists, oncologists, experimental therapeutic specialists, and others interested in glutathione S-transferases.

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CY - Baco Raton

ER -

Structure and Function of Glutathione S-Transferases

Abstract

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