Structure of trypanothione reductase from Crithidia fasciculata at 2.6 Angstroms resolution; Enzyme-NADP interactions at 2.8 Angstroms resolution

Keyphrases

• Crithidia Fasciculata 100%
• Trypanothione Reductase 100%
• Angstrom 100%
• Glutathione Reductase 80%
• Root Mean Square Deviation 60%
• Nicotinamide Adenine Dinucleotide Phosphate (NADPH) 40%
• Terminal Residue 40%
• Dinucleotide 40%
• Search Model 20%
• Protozoan Parasites 20%
• Leishmania 20%
• Loop Region 20%
• Trypanothione 20%
• Sequence Identity 20%
• Trypanosoma 20%
• Glutathionylspermidine 20%
• Adenosine 20%
• Binding Mode 20%
• Disulfide 20%
• Nicotinamide 20%
• Molecular Replacement 20%
• Prosthetic Group 20%
• Secondary Structural Elements 20%
• Bond Length 20%
• Solvent Molecules 20%
• Bond Angle 20%
• R-factor 20%
• Disulfide Oxidoreductase 20%
• Deviation from Ideality 20%
• Structural Units 20%

Biochemistry, Genetics and Molecular Biology

• Enzyme 100%
• Nicotinamide Adenine Dinucleotide Phosphate 100%
• Oxidoreductase 100%
• Reductase 100%
• Crithidia fasciculata 100%
• Trypanothione 100%
• Cofactor 66%
• Glutathione Reductase 66%
• Disulfide 33%
• C-Terminus 16%
• N-Terminus 16%
• Trypanosoma 16%
• Protozoon 16%
• Conformation 16%
• Leishmania 16%
• R-Factor 16%
• Adenosine 16%
• Nicotinamide 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Crithidia fasciculata 100%
• Trypanothione Reductase 100%
• Nicotinamide Adenine Dinucleotide Phosphate 100%
• Glutathione Reductase 80%
• Reduced Nicotinamide Adenine Dinucleotide Phosphate 40%
• Disulfide 40%
• Dinucleotide 40%
• Leishmania 20%
• Protozoon 20%
• Trypanothione 20%
• Trypanosoma 20%
• Adenosine 20%
• Nicotinamide 20%
• Oxidoreductase 20%
• R-Factor 20%
• Bond Length 20%