Structured Models of Cell Migration Incorporating Membrane Reactions (Keynote Speaker Talk)

Research output: Contribution to conferencePaper


The dynamic interplay between collective cell movement and the various molecules
involved in the accompanying cell signalling mechanisms plays a crucial role in many biological processes including normal tissue development and pathological scenarios such as wound healing and cancer. Information about the various structures embedded within these processes enables a detailed exploration of the binding of molecular species to cell-surface receptors within the evolving cell population. In this work we establish a general spatio-temporal-structural framework that enables the description of surface- bound reaction processes coupled with the cell population dynamics. We first provide a general theoretical description for this approach and then illustrate it with two concrete examples arising from cancer invasion.


ConferenceNew Mathematical and Computational Problems involved in Cell Motility, Morphogenesis and Pattern Formation
Country/TerritoryUnited Kingdom


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