The dynamic interplay between collective cell movement and the various molecules involved in the accompanying cell signalling mechanisms plays a crucial role in many biological processes including normal tissue development and pathological scenarios such as wound healing and cancer. Information about the various structures embedded within these processes enables a detailed exploration of the binding of molecular species to cell-surface receptors within the evolving cell population. In this work we establish a general spatio-temporal-structural framework that enables the description of surface-bound reaction processes coupled with the cell population dynamics. We first provide a general theoretical description for this approach and then illustrate it with concrete examples arising from cancer invasion.
|Publication status||Published - 2017|
|Event||Partial Differential Equations in Biology - University of Warwick, Coventry, United Kingdom|
Duration: 22 Jun 2017 → 23 Jun 2017
|Conference||Partial Differential Equations in Biology|
|City||University of Warwick, Coventry|
|Period||22/06/17 → 23/06/17|