Suicidal poisoning with mercaptodimethur: morphological findings and toxicological analysis

A. Thierauf, H. Gnann, M. Bohnert, B. Vennemann, V. Auwaerter, W. Weinmann

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    10 Citations (Scopus)

    Abstract

    In the western countries, the number of fatal intoxications with plant protecting agents has decreased to some extent due to laws restricting the use of highly toxic pesticides like halogenated hydrocarbons. Nevertheless, in consideration of the easy availability of most plant protectants, the small fraction of such fatalities among suicides and intoxications is astonishing. An 80-year-old woman died of an intoxication with methiocarb (mercaptodimethur), a carbamate type pesticide and as such a reversible inhibitor of the acetylcholinesterase. The case is presented because it is the first explicit report on a fatal poisoning of a human with methiocarb. The methiocarb concentrations detected were 6,100 mu g/g in stomach content, 4.0 mu g/ml in heart blood, 11 mu g/g in kidney, 1.9 mu g/ml in urine, 25 mu g/g in liver, 2 mu g/g in bile and 2.5 mu g/g in brain tissue.

    Original languageEnglish
    Pages (from-to)327-331
    Number of pages5
    JournalInternational Journal of Legal Medicine
    Volume123
    Issue number4
    DOIs
    Publication statusPublished - Jul 2009

    Keywords

    • Mercaptodimethur
    • Methiocarb
    • LC-MS/MS
    • Suicide
    • BODY

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