SUMO chain-induced dimerization activates RNF4

Search results

• Finished

  Dynamics of Fundamental Cellular Processes by Live Cell and Tissue Imaging

  MacDonald, M. (Investigator), McGloin, D. (Investigator), McKenna, S. (Investigator), Storey, K. (Investigator), Swedlow, J. (Investigator) & Weijer, K. (Investigator)

  Medical Research Council

  1/01/13 → 31/12/17

  Project: Research

  • Caenorhabditis Elegans 100%
  • Mitosis 52%
  • Dopaminergic 44%
  • 6-hydroxydopamine (6-OHDA) 42%
  • Trypanosoma 42%

• Strategic Award: Wellcome Trust Technology Platform

  Blow, J. (Investigator), Lamond, A. (Investigator) & Owen-Hughes, T. (Investigator)

  1/01/13 → 30/09/18

  Project: Research

  • Proteomics 100%
  • Ubiquitin 96%
  • Proteome 71%
  • Messenger RNA 59%
  • Chromatin 59%

• Determining the Role and Mechanism of Action of SUMO Targeted Ubiquitin Ligase RNF4 in Maintaining Genome Integrity (Senior Investigator Award)

  Hay, R. (Investigator)

  1/10/12 → 31/01/20

  Project: Research

  • Ubiquitin 100%
  • Ubiquitin-like 51%
  • Small Ubiquitin-like Modifier 45%
  • Ubiquitin Ligase 32%
  • Ubiquitin-Conjugating Enzyme 23%