Synergistic use of high-resolution flow-sensitive and flow-compensated MRI sequences for the evaluation of cerebrospinal fluid flow disorders

William Clackett; Avinash K. Kanodia; Heinke Pulhorn; Mohamed Okasha; Anna Solth; Anna Podlasek; Magdalena Szewczyk-Bieda; Riccardo Zannoni; Thiru Sudarshan; Iris Q. Grunwald

doi:10.1177/00369330251403510

Synergistic use of high-resolution flow-sensitive and flow-compensated MRI sequences for the evaluation of cerebrospinal fluid flow disorders

William Clackett
, Avinash K. Kanodia (Lead / Corresponding author)
, Heinke Pulhorn
, Mohamed Okasha
, Anna Solth
, Anna Podlasek
, Magdalena Szewczyk-Bieda
, Riccardo Zannoni
, Thiru Sudarshan
, Iris Q. Grunwald

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

In the assessment of cerebrospinal fluid flow disorders such as aqueductal stenosis, Chiari malformation, and post-operative complications, conventional imaging often falls short in resolving subtle anatomical and dynamic nuances. This case series explores the value of integrating high-resolution flow-sensitive and flow-compensated magnetic resonance imaging sequences to enhance diagnostic precision in challenging scenarios. Across five diverse cases, the combined approach revealed subtle aetiologies like prepontine adhesions, fourth ventricle outlet obstruction, aqueductal stenosis and minute dural breaches – all which were undetectable with routine conventional imaging.

Original language	English
Journal	Scottish Medical Journal
Early online date	8 Dec 2025
DOIs	https://doi.org/10.1177/00369330251403510
Publication status	E-pub ahead of print - 8 Dec 2025

Keywords

CSF flow disorders
high-resolution flow compensated
high-resolution flow sensitive

ASJC Scopus subject areas

General Medicine

Access to Document

10.1177/00369330251403510

Cite this

Clackett, W., Kanodia, A. K., Pulhorn, H., Okasha, M., Solth, A., Podlasek, A., Szewczyk-Bieda, M., Zannoni, R., Sudarshan, T., & Grunwald, I. Q. (2025). Synergistic use of high-resolution flow-sensitive and flow-compensated MRI sequences for the evaluation of cerebrospinal fluid flow disorders. Scottish Medical Journal. Advance online publication. https://doi.org/10.1177/00369330251403510

@article{702293f99b504cb1b612e6cf3c3389c2,

title = "Synergistic use of high-resolution flow-sensitive and flow-compensated MRI sequences for the evaluation of cerebrospinal fluid flow disorders",

abstract = "In the assessment of cerebrospinal fluid flow disorders such as aqueductal stenosis, Chiari malformation, and post-operative complications, conventional imaging often falls short in resolving subtle anatomical and dynamic nuances. This case series explores the value of integrating high-resolution flow-sensitive and flow-compensated magnetic resonance imaging sequences to enhance diagnostic precision in challenging scenarios. Across five diverse cases, the combined approach revealed subtle aetiologies like prepontine adhesions, fourth ventricle outlet obstruction, aqueductal stenosis and minute dural breaches – all which were undetectable with routine conventional imaging.",

keywords = "CSF flow disorders, high-resolution flow compensated, high-resolution flow sensitive",

author = "William Clackett and Kanodia, \{Avinash K.\} and Heinke Pulhorn and Mohamed Okasha and Anna Solth and Anna Podlasek and Magdalena Szewczyk-Bieda and Riccardo Zannoni and Thiru Sudarshan and Grunwald, \{Iris Q.\}",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2025",

year = "2025",

month = dec,

day = "8",

doi = "10.1177/00369330251403510",

language = "English",

journal = "Scottish Medical Journal",

issn = "0036-9330",

publisher = "SAGE Publications",

}

TY - JOUR

T1 - Synergistic use of high-resolution flow-sensitive and flow-compensated MRI sequences for the evaluation of cerebrospinal fluid flow disorders

AU - Clackett, William

AU - Kanodia, Avinash K.

AU - Pulhorn, Heinke

AU - Okasha, Mohamed

AU - Solth, Anna

AU - Podlasek, Anna

AU - Szewczyk-Bieda, Magdalena

AU - Zannoni, Riccardo

AU - Sudarshan, Thiru

AU - Grunwald, Iris Q.

PY - 2025/12/8

Y1 - 2025/12/8

N2 - In the assessment of cerebrospinal fluid flow disorders such as aqueductal stenosis, Chiari malformation, and post-operative complications, conventional imaging often falls short in resolving subtle anatomical and dynamic nuances. This case series explores the value of integrating high-resolution flow-sensitive and flow-compensated magnetic resonance imaging sequences to enhance diagnostic precision in challenging scenarios. Across five diverse cases, the combined approach revealed subtle aetiologies like prepontine adhesions, fourth ventricle outlet obstruction, aqueductal stenosis and minute dural breaches – all which were undetectable with routine conventional imaging.

AB - In the assessment of cerebrospinal fluid flow disorders such as aqueductal stenosis, Chiari malformation, and post-operative complications, conventional imaging often falls short in resolving subtle anatomical and dynamic nuances. This case series explores the value of integrating high-resolution flow-sensitive and flow-compensated magnetic resonance imaging sequences to enhance diagnostic precision in challenging scenarios. Across five diverse cases, the combined approach revealed subtle aetiologies like prepontine adhesions, fourth ventricle outlet obstruction, aqueductal stenosis and minute dural breaches – all which were undetectable with routine conventional imaging.

KW - CSF flow disorders

KW - high-resolution flow compensated

KW - high-resolution flow sensitive

UR - https://www.scopus.com/pages/publications/105024195981

U2 - 10.1177/00369330251403510

DO - 10.1177/00369330251403510

M3 - Article

C2 - 41359306

AN - SCOPUS:105024195981

SN - 0036-9330

JO - Scottish Medical Journal

JF - Scottish Medical Journal

ER -

Synergistic use of high-resolution flow-sensitive and flow-compensated MRI sequences for the evaluation of cerebrospinal fluid flow disorders

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this