The synthesis and characterisation of a novel iodinated bile salt derivative, 125I-labelled 3ß-azidocholylhistamine, is described. The derivative is handled by rat liver in a similar manner to taurocholate and binding to bovine serum albumin, a well-characterised bile acid-binding protein, is demonstrated. The suitability of the derivative for photoaffinity labelling is assessed.
|Number of pages||8|
|Journal||Biochimica et Biophysica Acta. Lipids and Lipid Metabolism|
|Publication status||Published - 12 Sep 1984|
- Bile salt
- Photoaffinity labelling
- Rat liver